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Mechanism of action and therapeutic route for a muscular dystrophy caused by a genetic defect in lipid metabolism.
Tavasoli M, Lahire S, Sokolenko S, Novorolsky R, Reid SA, Lefsay A, Otley MOC, Uaesoontrachoon K, Rowsell J, Srinivassane S, Praest M, MacKinnon A, Mammoliti MS, Maloney AA, Moraca M, Pedro Fernandez-Murray J, McKenna M, Sinal CJ, Nagaraju K, Robertson GS, Hoffman EP, McMaster CR. Tavasoli M, et al. Among authors: moraca m. Nat Commun. 2022 Mar 23;13(1):1559. doi: 10.1038/s41467-022-29270-z. Nat Commun. 2022. PMID: 35322809 Free PMC article.
A mouse model of inherited choline kinase β-deficiency presents with specific cardiac abnormalities and a predisposition to arrhythmia.
Tavasoli M, Feridooni T, Feridooni H, Sokolenko S, Mishra A, Lefsay A, Srinivassane S, Reid SA, Rowsell J, Praest M, MacKinnon A, Mammoliti M, Maloney AA, Moraca M, Uaesoontrachoon K, Nagaraju K, Hoffman EP, Pasumarthi KBS, McMaster CR. Tavasoli M, et al. Among authors: moraca m. J Biol Chem. 2022 Mar;298(3):101716. doi: 10.1016/j.jbc.2022.101716. Epub 2022 Feb 11. J Biol Chem. 2022. PMID: 35151687 Free PMC article.
Orthogonal analysis of dystrophin protein and mRNA as a surrogate outcome for drug development.
Uaesoontrachoon K, Srinivassane S, Warford J, Mekhssian K, Montpetit H, Beauvois R, Keyhani A, Hathout Y, Yamashita T, Satou Y, Osaki H, Praest M, Moraca M, Malbasic M, Ross W, MacKinnon A, Rowsell J, Mullen A, Matyas M, Mummidivarpu S, Nagaraju K, Hoffman EP. Uaesoontrachoon K, et al. Among authors: moraca m. Biomark Med. 2019 Oct;13(14):1209-1225. doi: 10.2217/bmm-2019-0242. Epub 2019 Aug 5. Biomark Med. 2019. PMID: 31379197 Free article.
The UP-TECH project, an intervention to support caregivers of Alzheimer's disease patients in Italy: preliminary findings on recruitment and caregiving burden in the baseline population.
Chiatti C, Rimland JM, Bonfranceschi F, Masera F, Bustacchini S, Cassetta L; Fabrizia Lattanzio; UP-TECH research group. Chiatti C, et al. Aging Ment Health. 2015;19(6):517-25. doi: 10.1080/13607863.2014.954526. Epub 2014 Sep 4. Aging Ment Health. 2015. PMID: 25188811 Clinical Trial.
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