Keller JN - Search Results

1

Oleocanthal enhances amyloid-β clearance from the brains of TgSwDI mice and in vitro across a human blood-brain barrier model.

Qosa H, Batarseh YS, Mohyeldin MM, El Sayed KA, Keller JN, Kaddoumi A. Qosa H, et al. Among authors: keller jn. ACS Chem Neurosci. 2015 Nov 18;6(11):1849-59. doi: 10.1021/acschemneuro.5b00190. Epub 2015 Sep 16. ACS Chem Neurosci. 2015. PMID: 26348065 Free PMC article.

2

Prolonged diet induced obesity has minimal effects towards brain pathology in mouse model of cerebral amyloid angiopathy: implications for studying obesity-brain interactions in mice.

Zhang L, Dasuri K, Fernandez-Kim SO, Bruce-Keller AJ, Freeman LR, Pepping JK, Beckett TL, Murphy MP, Keller JN. Zhang L, et al. Among authors: keller jn. Biochim Biophys Acta. 2013 Sep;1832(9):1456-62. doi: 10.1016/j.bbadis.2013.01.002. Epub 2013 Jan 9. Biochim Biophys Acta. 2013. PMID: 23313575 Free PMC article.

3

Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling.

Qosa H, Abuasal BS, Romero IA, Weksler B, Couraud PO, Keller JN, Kaddoumi A. Qosa H, et al. Among authors: keller jn. Neuropharmacology. 2014 Apr;79:668-78. doi: 10.1016/j.neuropharm.2014.01.023. Epub 2014 Jan 24. Neuropharmacology. 2014. PMID: 24467845 Free PMC article.

4

Mixed oligomers and monomeric amyloid-β disrupts endothelial cells integrity and reduces monomeric amyloid-β transport across hCMEC/D3 cell line as an in vitro blood-brain barrier model.

Qosa H, LeVine H 3rd, Keller JN, Kaddoumi A. Qosa H, et al. Among authors: keller jn. Biochim Biophys Acta. 2014 Sep;1842(9):1806-15. doi: 10.1016/j.bbadis.2014.06.029. Epub 2014 Jul 2. Biochim Biophys Acta. 2014. PMID: 24997450 Free PMC article.

5

Extra-virgin olive oil attenuates amyloid-β and tau pathologies in the brains of TgSwDI mice.

Qosa H, Mohamed LA, Batarseh YS, Alqahtani S, Ibrahim B, LeVine H 3rd, Keller JN, Kaddoumi A. Qosa H, et al. Among authors: keller jn. J Nutr Biochem. 2015 Dec;26(12):1479-90. doi: 10.1016/j.jnutbio.2015.07.022. Epub 2015 Aug 13. J Nutr Biochem. 2015. PMID: 26344778 Free PMC article.

6

Role of P-glycoprotein in mediating rivastigmine effect on amyloid-β brain load and related pathology in Alzheimer's disease mouse model.

Mohamed LA, Keller JN, Kaddoumi A. Mohamed LA, et al. Among authors: keller jn. Biochim Biophys Acta. 2016 Apr;1862(4):778-787. doi: 10.1016/j.bbadis.2016.01.013. Epub 2016 Jan 15. Biochim Biophys Acta. 2016. PMID: 26780497 Free PMC article.

7

High-Throughput Screening for Identification of Blood-Brain Barrier Integrity Enhancers: A Drug Repurposing Opportunity to Rectify Vascular Amyloid Toxicity.

Qosa H, Mohamed LA, Al Rihani SB, Batarseh YS, Duong QV, Keller JN, Kaddoumi A. Qosa H, et al. Among authors: keller jn. J Alzheimers Dis. 2016 Jul 6;53(4):1499-516. doi: 10.3233/JAD-151179. J Alzheimers Dis. 2016. PMID: 27392852 Free PMC article.

8

Proteasome inhibition modulates kinase activation in neural cells: relevance to ubiquitination, ribosomes, and survival.

Zhang L, Ebenezer PJ, Dasuri K, Bruce-Keller AJ, Liu Y, Keller JN. Zhang L, et al. Among authors: keller jn. J Neurosci Res. 2009 Nov 1;87(14):3231-8. doi: 10.1002/jnr.22147. J Neurosci Res. 2009. PMID: 19565657 Free PMC article.

9

NOX activity is increased in mild cognitive impairment.

Bruce-Keller AJ, Gupta S, Parrino TE, Knight AG, Ebenezer PJ, Weidner AM, LeVine H 3rd, Keller JN, Markesbery WR. Bruce-Keller AJ, et al. Among authors: keller jn. Antioxid Redox Signal. 2010 Jun 15;12(12):1371-82. doi: 10.1089/ars.2009.2823. Antioxid Redox Signal. 2010. PMID: 19929442 Free PMC article.

10

Increased protein hydrophobicity in response to aging and Alzheimer disease.

Dasuri K, Ebenezer P, Zhang L, Fernandez-Kim SO, Bruce-Keller AJ, Markesbery WR, Keller JN. Dasuri K, et al. Among authors: keller jn. Free Radic Biol Med. 2010 May 15;48(10):1330-7. doi: 10.1016/j.freeradbiomed.2010.02.012. Epub 2010 Feb 24. Free Radic Biol Med. 2010. PMID: 20188163 Free PMC article.

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