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Dissecting the role of epidermal growth factor receptor catalytic activity during liver regeneration and hepatocarcinogenesis.
López-Luque J, Caballero-Díaz D, Martinez-Palacián A, Roncero C, Moreno-Càceres J, García-Bravo M, Grueso E, Fernández A, Crosas-Molist E, García-Álvaro M, Addante A, Bertran E, Valverde AM, González-Rodríguez Á, Herrera B, Montoliu L, Serrano T, Segovia JC, Fernández M, Ramos E, Sánchez A, Fabregat I. López-Luque J, et al. Among authors: addante a. Hepatology. 2016 Feb;63(2):604-19. doi: 10.1002/hep.28134. Epub 2015 Oct 10. Hepatology. 2016. PMID: 26313466
c-Met Signaling Is Essential for Mouse Adult Liver Progenitor Cells Expansion After Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition and Regulates Cell Phenotypic Switch.
Almalé L, García-Álvaro M, Martínez-Palacián A, García-Bravo M, Lazcanoiturburu N, Addante A, Roncero C, Sanz J, de la O López M, Bragado P, Mikulits W, Factor VM, Thorgeirsson SS, Casal JI, Segovia JC, Rial E, Fabregat I, Herrera B, Sánchez A. Almalé L, et al. Among authors: addante a. Stem Cells. 2019 Aug;37(8):1108-1118. doi: 10.1002/stem.3038. Epub 2019 Jun 18. Stem Cells. 2019. PMID: 31108004
Clathrin switches transforming growth factor-β role to pro-tumorigenic in liver cancer.
Caballero-Díaz D, Bertran E, Peñuelas-Haro I, Moreno-Càceres J, Malfettone A, López-Luque J, Addante A, Herrera B, Sánchez A, Alay A, Solé X, Serrano T, Ramos E, Fabregat I. Caballero-Díaz D, et al. Among authors: addante a. J Hepatol. 2020 Jan;72(1):125-134. doi: 10.1016/j.jhep.2019.09.012. Epub 2019 Sep 25. J Hepatol. 2020. PMID: 31562907 Free article.
HGF/c-Met signaling promotes liver progenitor cell migration and invasion by an epithelial-mesenchymal transition-independent, phosphatidyl inositol-3 kinase-dependent pathway in an in vitro model.
Suárez-Causado A, Caballero-Díaz D, Bertrán E, Roncero C, Addante A, García-Álvaro M, Fernández M, Herrera B, Porras A, Fabregat I, Sánchez A. Suárez-Causado A, et al. Among authors: addante a. Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2453-63. doi: 10.1016/j.bbamcr.2015.05.017. Epub 2015 May 20. Biochim Biophys Acta. 2015. PMID: 26001768 Free article.
BMP-9 interferes with liver regeneration and promotes liver fibrosis.
Breitkopf-Heinlein K, Meyer C, König C, Gaitantzi H, Addante A, Thomas M, Wiercinska E, Cai C, Li Q, Wan F, Hellerbrand C, Valous NA, Hahnel M, Ehlting C, Bode JG, Müller-Bohl S, Klingmüller U, Altenöder J, Ilkavets I, Goumans MJ, Hawinkels LJ, Lee SJ, Wieland M, Mogler C, Ebert MP, Herrera B, Augustin H, Sánchez A, Dooley S, Ten Dijke P. Breitkopf-Heinlein K, et al. Among authors: addante a. Gut. 2017 May;66(5):939-954. doi: 10.1136/gutjnl-2016-313314. Epub 2017 Mar 23. Gut. 2017. PMID: 28336518
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