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Page 1
Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity.
Jabouille A, Delugin M, Pineau R, Dubrac A, Soulet F, Lhomond S, Pallares-Lupon N, Prats H, Bikfalvi A, Chevet E, Touriol C, Moenner M. Jabouille A, et al. Among authors: pineau r. Oncotarget. 2015 Sep 22;6(28):24922-34. doi: 10.18632/oncotarget.4679. Oncotarget. 2015. PMID: 26325176 Free PMC article.
Dual IRE1 RNase functions dictate glioblastoma development.
Lhomond S, Avril T, Dejeans N, Voutetakis K, Doultsinos D, McMahon M, Pineau R, Obacz J, Papadodima O, Jouan F, Bourien H, Logotheti M, Jégou G, Pallares-Lupon N, Schmit K, Le Reste PJ, Etcheverry A, Mosser J, Barroso K, Vauléon E, Maurel M, Samali A, Patterson JB, Pluquet O, Hetz C, Quillien V, Chatziioannou A, Chevet E. Lhomond S, et al. Among authors: pineau r. EMBO Mol Med. 2018 Mar;10(3):e7929. doi: 10.15252/emmm.201707929. EMBO Mol Med. 2018. PMID: 29311133 Free PMC article.
Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma.
Auf G, Jabouille A, Guérit S, Pineau R, Delugin M, Bouchecareilh M, Magnin N, Favereaux A, Maitre M, Gaiser T, von Deimling A, Czabanka M, Vajkoczy P, Chevet E, Bikfalvi A, Moenner M. Auf G, et al. Among authors: pineau r. Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15553-8. doi: 10.1073/pnas.0914072107. Epub 2010 Aug 11. Proc Natl Acad Sci U S A. 2010. PMID: 20702765 Free PMC article.
Posttranscriptional regulation of PER1 underlies the oncogenic function of IREα.
Pluquet O, Dejeans N, Bouchecareilh M, Lhomond S, Pineau R, Higa A, Delugin M, Combe C, Loriot S, Cubel G, Dugot-Senant N, Vital A, Loiseau H, Gosline SJ, Taouji S, Hallett M, Sarkaria JN, Anderson K, Wu W, Rodriguez FJ, Rosenbaum J, Saltel F, Fernandez-Zapico ME, Chevet E. Pluquet O, et al. Among authors: pineau r. Cancer Res. 2013 Aug 1;73(15):4732-43. doi: 10.1158/0008-5472.CAN-12-3989. Epub 2013 Jun 10. Cancer Res. 2013. PMID: 23752693 Free PMC article.
Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5.
Exertier P, Javerzat S, Wang B, Franco M, Herbert J, Platonova N, Winandy M, Pujol N, Nivelles O, Ormenese S, Godard V, Becker J, Bicknell R, Pineau R, Wilting J, Bikfalvi A, Hagedorn M. Exertier P, et al. Among authors: pineau r. Oncotarget. 2013 Dec;4(12):2302-16. doi: 10.18632/oncotarget.1490. Oncotarget. 2013. PMID: 24327603 Free PMC article.
Dual Roles for CXCL4 Chemokines and CXCR3 in Angiogenesis and Invasion of Pancreatic Cancer.
Quemener C, Baud J, Boyé K, Dubrac A, Billottet C, Soulet F, Darlot F, Dumartin L, Sire M, Grepin R, Daubon T, Rayne F, Wodrich H, Couvelard A, Pineau R, Schilling M, Castronovo V, Sue SC, Clarke K, Lomri A, Khatib AM, Hagedorn M, Prats H, Bikfalvi A. Quemener C, et al. Among authors: pineau r. Cancer Res. 2016 Nov 15;76(22):6507-6519. doi: 10.1158/0008-5472.CAN-15-2864. Epub 2016 Sep 9. Cancer Res. 2016. PMID: 27634764 Free article.
Local intracerebral inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo.
Le Reste PJ, Pineau R, Voutetakis K, Samal J, Jégou G, Lhomond S, Gorman AM, Samali A, Patterson JB, Zeng Q, Pandit A, Aubry M, Soriano N, Etcheverry A, Chatziioannou A, Mosser J, Avril T, Chevet E. Le Reste PJ, et al. Among authors: pineau r. Cancer Lett. 2020 Dec 1;494:73-83. doi: 10.1016/j.canlet.2020.08.028. Epub 2020 Sep 1. Cancer Lett. 2020. PMID: 32882336
68 results