Kini RM - Search Results

1

Microfluidic Chip-Based Online Screening Coupled to Mass Spectrometry: Identification of Inhibitors of Thrombin and Factor Xa.

Iyer JK, Otvos RA, Kool J, Kini RM. Iyer JK, et al. Among authors: kini rm. J Biomol Screen. 2016 Feb;21(2):212-20. doi: 10.1177/1087057115602648. Epub 2015 Aug 31. J Biomol Screen. 2016. PMID: 26323281

2

Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms.

Otvos RA, Iyer JK, van Elk R, Ulens C, Niessen WM, Somsen GW, Kini RM, Smit AB, Kool J. Otvos RA, et al. Among authors: kini rm. Toxins (Basel). 2015 Jun 24;7(7):2336-53. doi: 10.3390/toxins7072336. Toxins (Basel). 2015. PMID: 26114334 Free PMC article.

3

Unveiling the complexities of Daboia russelii venom, a medically important snake of India, by tandem mass spectrometry.

Sharma M, Das D, Iyer JK, Kini RM, Doley R. Sharma M, et al. Among authors: kini rm. Toxicon. 2015 Dec 1;107(Pt B):266-81. doi: 10.1016/j.toxicon.2015.06.027. Epub 2015 Jul 6. Toxicon. 2015. PMID: 26160495

4

At-line nanofractionation with parallel mass spectrometry and bioactivity assessment for the rapid screening of thrombin and factor Xa inhibitors in snake venoms.

Mladic M, Zietek BM, Iyer JK, Hermarij P, Niessen WM, Somsen GW, Kini RM, Kool J. Mladic M, et al. Among authors: kini rm. Toxicon. 2016 Feb;110:79-89. doi: 10.1016/j.toxicon.2015.12.008. Epub 2015 Dec 19. Toxicon. 2016. PMID: 26708656

5

Development of an Online Cell-Based Bioactivity Screening Method by Coupling Liquid Chromatography to Flow Cytometry with Parallel Mass Spectrometry.

Otvos RA, van Nierop P, Niessen WM, Kini RM, Somsen GW, Smit AB, Kool J. Otvos RA, et al. Among authors: kini rm. Anal Chem. 2016 May 3;88(9):4825-32. doi: 10.1021/acs.analchem.6b00455. Epub 2016 Apr 20. Anal Chem. 2016. PMID: 27046509

6

Avathrin: a novel thrombin inhibitor derived from a multicopy precursor in the salivary glands of the ixodid tick, Amblyomma variegatum.

Iyer JK, Koh CY, Kazimirova M, Roller L, Jobichen C, Swaminathan K, Mizuguchi J, Iwanaga S, Nuttall PA, Chan MY, Kini RM. Iyer JK, et al. Among authors: kini rm. FASEB J. 2017 Jul;31(7):2981-2995. doi: 10.1096/fj.201601216R. Epub 2017 Mar 31. FASEB J. 2017. PMID: 28363953

7

Neurotoxicity fingerprinting of venoms using on-line microfluidic AChBP profiling.

Slagboom J, Otvos RA, Cardoso FC, Iyer J, Visser JC, van Doodewaerd BR, McCleary RJR, Niessen WMA, Somsen GW, Lewis RJ, Kini RM, Smit AB, Casewell NR, Kool J. Slagboom J, et al. Among authors: kini rm. Toxicon. 2018 Jun 15;148:213-222. doi: 10.1016/j.toxicon.2018.04.022. Epub 2018 May 4. Toxicon. 2018. PMID: 29730150 Free article.

8

Efficacy and safety of next-generation tick transcriptome-derived direct thrombin inhibitors.

Koh CY, Shih N, Yip CYC, Li AWL, Chen W, Amran FS, Leong EJE, Iyer JK, Croft G, Mazlan MIB, Chee YL, Yap ES, Monroe DM, Hoffman M, Becker RC, de Kleijn DPV, Verma V, Gupta A, Chaudhary VK, Richards AM, Kini RM, Chan MY. Koh CY, et al. Among authors: kini rm. Nat Commun. 2021 Nov 25;12(1):6912. doi: 10.1038/s41467-021-27275-8. Nat Commun. 2021. PMID: 34824278 Free PMC article.

9

Effects of tannins from Geum japonicum on the catalytic activity of thrombin and factor Xa of blood coagulation cascade.

Dong H, Chen SX, Kini RM, Xu HX. Dong H, et al. Among authors: kini rm. J Nat Prod. 1998 Nov;61(11):1356-60. doi: 10.1021/np9801458. J Nat Prod. 1998. PMID: 9834152

10

Rapid simultaneous detection of two orchid viruses using LC- and/or MALDI-mass spectrometry.

Tan SW, Wong SM, Kini RM. Tan SW, et al. Among authors: kini rm. J Virol Methods. 2000 Mar;85(1-2):93-9. doi: 10.1016/s0166-0934(99)00157-3. J Virol Methods. 2000. PMID: 10716342

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