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Characterization of 2,4-Diamino-6-oxo-1,6-dihydropyrimidin-5-yl Ureido Based Inhibitors of Trypanosoma brucei FolD and Testing for Antiparasitic Activity.
Eadsforth TC, Pinto A, Luciani R, Tamborini L, Cullia G, De Micheli C, Marinelli L, Cosconati S, Novellino E, Lo Presti L, Cordeiro da Silva A, Conti P, Hunter WN, Costi MP. Eadsforth TC, et al. Among authors: lo presti l. J Med Chem. 2015 Oct 22;58(20):7938-48. doi: 10.1021/acs.jmedchem.5b00687. Epub 2015 Sep 16. J Med Chem. 2015. PMID: 26322631 Free PMC article.
Synthesis and biological evaluation of CTP synthetase inhibitors as potential agents for the treatment of African trypanosomiasis.
Tamborini L, Pinto A, Smith TK, Major LL, Iannuzzi MC, Cosconati S, Marinelli L, Novellino E, Lo Presti L, Wong PE, Barrett MP, De Micheli C, Conti P. Tamborini L, et al. Among authors: lo presti l. ChemMedChem. 2012 Sep;7(9):1623-34. doi: 10.1002/cmdc.201200304. Epub 2012 Aug 2. ChemMedChem. 2012. PMID: 22865834 Free PMC article.
Development of rhodesain inhibitors with a 3-bromoisoxazoline warhead.
Ettari R, Tamborini L, Angelo IC, Grasso S, Schirmeister T, Lo Presti L, De Micheli C, Pinto A, Conti P. Ettari R, et al. Among authors: lo presti l. ChemMedChem. 2013 Dec;8(12):2070-6. doi: 10.1002/cmdc.201300390. Epub 2013 Nov 15. ChemMedChem. 2013. PMID: 24243827
4-(1,2-diarylbut-1-en-1-yl)isobutyranilide derivatives as inhibitors of topoisomerase II.
Christodoulou MS, Zarate M, Ricci F, Damia G, Pieraccini S, Dapiaggi F, Sironi M, Lo Presti L, García-Argáez AN, Dalla Via L, Passarella D. Christodoulou MS, et al. Among authors: lo presti l. Eur J Med Chem. 2016 Aug 8;118:79-89. doi: 10.1016/j.ejmech.2016.03.090. Epub 2016 Apr 11. Eur J Med Chem. 2016. PMID: 27128175
110 results