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Characterization of 2,4-Diamino-6-oxo-1,6-dihydropyrimidin-5-yl Ureido Based Inhibitors of Trypanosoma brucei FolD and Testing for Antiparasitic Activity.
Eadsforth TC, Pinto A, Luciani R, Tamborini L, Cullia G, De Micheli C, Marinelli L, Cosconati S, Novellino E, Lo Presti L, Cordeiro da Silva A, Conti P, Hunter WN, Costi MP. Eadsforth TC, et al. Among authors: de micheli c. J Med Chem. 2015 Oct 22;58(20):7938-48. doi: 10.1021/acs.jmedchem.5b00687. Epub 2015 Sep 16. J Med Chem. 2015. PMID: 26322631 Free PMC article.
Design and synthesis of novel isoxazole-based HDAC inhibitors.
Conti P, Tamborini L, Pinto A, Sola L, Ettari R, Mercurio C, De Micheli C. Conti P, et al. Among authors: de micheli c. Eur J Med Chem. 2010 Sep;45(9):4331-8. doi: 10.1016/j.ejmech.2010.06.035. Epub 2010 Jun 30. Eur J Med Chem. 2010. PMID: 20637529
Synthesis and biological evaluation of CTP synthetase inhibitors as potential agents for the treatment of African trypanosomiasis.
Tamborini L, Pinto A, Smith TK, Major LL, Iannuzzi MC, Cosconati S, Marinelli L, Novellino E, Lo Presti L, Wong PE, Barrett MP, De Micheli C, Conti P. Tamborini L, et al. Among authors: de micheli c. ChemMedChem. 2012 Sep;7(9):1623-34. doi: 10.1002/cmdc.201200304. Epub 2012 Aug 2. ChemMedChem. 2012. PMID: 22865834 Free PMC article.
Bicyclic γ-amino acids as inhibitors of γ-aminobutyrate aminotransferase.
Pinto A, Tamborini L, Pennacchietti E, Coluccia A, Silvestri R, Cullia G, De Micheli C, Conti P, De Biase D. Pinto A, et al. Among authors: de biase d, de micheli c. J Enzyme Inhib Med Chem. 2016;31(2):295-301. doi: 10.3109/14756366.2015.1021251. Epub 2015 Sep 25. J Enzyme Inhib Med Chem. 2016. PMID: 25807299 Free article.
Development of novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation.
Ettari R, Pinto A, Previti S, Tamborini L, Angelo IC, La Pietra V, Marinelli L, Novellino E, Schirmeister T, Zappalà M, Grasso S, De Micheli C, Conti P. Ettari R, et al. Among authors: de micheli c. Bioorg Med Chem. 2015 Nov 1;23(21):7053-60. doi: 10.1016/j.bmc.2015.09.029. Epub 2015 Sep 21. Bioorg Med Chem. 2015. PMID: 26432608
91 results