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MiR-93 Controls Adiposity via Inhibition of Sirt7 and Tbx3.
Cioffi M, Vallespinos-Serrano M, Trabulo SM, Fernandez-Marcos PJ, Firment AN, Vazquez BN, Vieira CR, Mulero F, Camara JA, Cronin UP, Perez M, Soriano J, G Galvez B, Castells-Garcia A, Haage V, Raj D, Megias D, Hahn S, Serrano L, Moon A, Aicher A, Heeschen C. Cioffi M, et al. Among authors: megias d. Cell Rep. 2015 Sep 8;12(10):1594-605. doi: 10.1016/j.celrep.2015.08.006. Epub 2015 Aug 28. Cell Rep. 2015. PMID: 26321631 Free article.
Phosphoproteomic analysis of neoadjuvant breast cancer suggests that increased sensitivity to paclitaxel is driven by CDK4 and filamin A.
Mouron S, Bueno MJ, Lluch A, Manso L, Calvo I, Cortes J, Garcia-Saenz JA, Gil-Gil M, Martinez-Janez N, Apala JV, Caleiras E, Ximénez-Embún P, Muñoz J, Gonzalez-Cortijo L, Murillo R, Sánchez-Bayona R, Cejalvo JM, Gómez-López G, Fustero-Torre C, Sabroso-Lasa S, Malats N, Martinez M, Moreno A, Megias D, Malumbres M, Colomer R, Quintela-Fandino M. Mouron S, et al. Among authors: megias d. Nat Commun. 2022 Dec 7;13(1):7529. doi: 10.1038/s41467-022-35065-z. Nat Commun. 2022. PMID: 36477027 Free PMC article.
Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK.
Maraver A, Fernández-Marcos PJ, Herranz D, Muñoz-Martin M, Gomez-Lopez G, Cañamero M, Mulero F, Megías D, Sanchez-Carbayo M, Shen J, Sanchez-Cespedes M, Palomero T, Ferrando A, Serrano M. Maraver A, et al. Among authors: megias d. Cancer Cell. 2012 Aug 14;22(2):222-34. doi: 10.1016/j.ccr.2012.06.014. Cancer Cell. 2012. PMID: 22897852 Free PMC article.
Intracellular autofluorescence: a biomarker for epithelial cancer stem cells.
Miranda-Lorenzo I, Dorado J, Lonardo E, Alcala S, Serrano AG, Clausell-Tormos J, Cioffi M, Megias D, Zagorac S, Balic A, Hidalgo M, Erkan M, Kleeff J, Scarpa A, Sainz B Jr, Heeschen C. Miranda-Lorenzo I, et al. Among authors: megias d. Nat Methods. 2014 Nov;11(11):1161-9. doi: 10.1038/nmeth.3112. Epub 2014 Sep 28. Nat Methods. 2014. PMID: 25262208
AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest.
Doménech E, Maestre C, Esteban-Martínez L, Partida D, Pascual R, Fernández-Miranda G, Seco E, Campos-Olivas R, Pérez M, Megias D, Allen K, López M, Saha AK, Velasco G, Rial E, Méndez R, Boya P, Salazar-Roa M, Malumbres M. Doménech E, et al. Among authors: megias d. Nat Cell Biol. 2015 Oct;17(10):1304-16. doi: 10.1038/ncb3231. Epub 2015 Aug 31. Nat Cell Biol. 2015. PMID: 26322680
The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1.
Cioffi M, Trabulo SM, Vallespinos M, Raj D, Kheir TB, Lin ML, Begum J, Baker AM, Amgheib A, Saif J, Perez M, Soriano J, Desco M, Gomez-Gaviro MV, Cusso L, Megias D, Aicher A, Heeschen C. Cioffi M, et al. Among authors: megias d. Oncotarget. 2017 Mar 28;8(13):21609-21625. doi: 10.18632/oncotarget.15450. Oncotarget. 2017. PMID: 28423491 Free PMC article.
112 results