Liu J - Search Results

1

Functional importance of a peripheral pocket in mammalian cytochrome P450 2B enzymes.

Jang HH, Liu J, Lee GY, Halpert JR, Wilderman PR. Jang HH, et al. Among authors: liu j. Arch Biochem Biophys. 2015 Oct 15;584:61-9. doi: 10.1016/j.abb.2015.08.007. Epub 2015 Aug 28. Arch Biochem Biophys. 2015. PMID: 26319176 Free PMC article.

2

Structural and biophysical characterization of human cytochromes P450 2B6 and 2A6 bound to volatile hydrocarbons: analysis and comparison.

Shah MB, Wilderman PR, Liu J, Jang HH, Zhang Q, Stout CD, Halpert JR. Shah MB, et al. Among authors: liu j. Mol Pharmacol. 2015 Apr;87(4):649-59. doi: 10.1124/mol.114.097014. Epub 2015 Jan 13. Mol Pharmacol. 2015. PMID: 25585967 Free PMC article.

3

Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations.

Liu J, Shah MB, Zhang Q, Stout CD, Halpert JR, Wilderman PR. Liu J, et al. Biochemistry. 2016 Apr 5;55(13):1997-2007. doi: 10.1021/acs.biochem.5b01330. Epub 2016 Mar 24. Biochemistry. 2016. PMID: 26982502 Free PMC article.

4

Halogen-π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity.

Shah MB, Liu J, Zhang Q, Stout CD, Halpert JR. Shah MB, et al. Among authors: liu j. ACS Chem Biol. 2017 May 19;12(5):1204-1210. doi: 10.1021/acschembio.7b00056. Epub 2017 Apr 6. ACS Chem Biol. 2017. PMID: 28368100 Free PMC article.

5

Rational Re-Engineering of the O-Dealkylation of 7-Alkoxycoumarin Derivatives by Cytochromes P450 2B from the Desert Woodrat Neotoma lepida.

Huo L, Liu J, Dearing MD, Szklarz GD, Halpert JR, Wilderman PR. Huo L, et al. Among authors: liu j. Biochemistry. 2017 Apr 25;56(16):2238-2246. doi: 10.1021/acs.biochem.7b00097. Epub 2017 Apr 12. Biochemistry. 2017. PMID: 28375626

6

Use of Phenoxyaniline Analogues To Generate Biochemical Insights into the Interactio n of Polybrominated Diphenyl Ether with CYP2B Enzymes.

Chen C, Liu J, Halpert JR, Wilderman PR. Chen C, et al. Among authors: liu j. Biochemistry. 2018 Feb 6;57(5):817-826. doi: 10.1021/acs.biochem.7b01024. Epub 2017 Dec 19. Biochemistry. 2018. PMID: 29215266 Free PMC article.

7

Role of residue 480 in substrate specificity of cytochrome P450 2B5 and 2B11.

Liu J, He YA, Halpert JR. Liu J, et al. Arch Biochem Biophys. 1996 Mar 1;327(1):167-73. doi: 10.1006/abbi.1996.0105. Arch Biochem Biophys. 1996. PMID: 8615687

8

Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism.

Shah MB, Liu J, Huo L, Zhang Q, Dearing MD, Wilderman PR, Szklarz GD, Stout CD, Halpert JR. Shah MB, et al. Among authors: liu j. Mol Pharmacol. 2016 Apr;89(4):435-45. doi: 10.1124/mol.115.102111. Epub 2016 Jan 29. Mol Pharmacol. 2016. PMID: 26826176 Free PMC article.

9

Analysis of four residues within substrate recognition site 4 of human cytochrome P450 3A4: role in steroid hydroxylase activity and alpha-naphthoflavone stimulation.

Domanski TL, Liu J, Harlow GR, Halpert JR. Domanski TL, et al. Among authors: liu j. Arch Biochem Biophys. 1998 Feb 15;350(2):223-32. doi: 10.1006/abbi.1997.0525. Arch Biochem Biophys. 1998. PMID: 9473295

10

Induction of cytochrome P-450 enzymes after repeated exposure to 4-vinylcyclohexene in B6C3F1 mice.

Doerr-Stevens JK, Liu J, Stevens GJ, Kraner JC, Fontaine SM, Halpert JR, Sipes IG. Doerr-Stevens JK, et al. Among authors: liu j. Drug Metab Dispos. 1999 Feb;27(2):281-7. Drug Metab Dispos. 1999. PMID: 9929517

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