Page B - Search Results

1

STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation.

Singh M, Garg N, Venugopal C, Hallett R, Tokar T, McFarlane N, Mahendram S, Bakhshinyan D, Manoranjan B, Vora P, Qazi M, Arpin CC, Page B, Haftchenary S, Rosa DA, Lai PS, Gómez-Biagi RF, Ali AM, Lewis A, Geletu M, Murty NK, Hassell JA, Jurisica I, Gunning PT, Singh SK. Singh M, et al. Among authors: page b. Oncotarget. 2015 Sep 29;6(29):27461-77. doi: 10.18632/oncotarget.4742. Oncotarget. 2015. PMID: 26314961 Free PMC article.

2

Disruption of transcriptionally active Stat3 dimers with non-phosphorylated, salicylic acid-based small molecules: potent in vitro and tumor cell activities.

Fletcher S, Singh J, Zhang X, Yue P, Page BD, Sharmeen S, Shahani VM, Zhao W, Schimmer AD, Turkson J, Gunning PT. Fletcher S, et al. Chembiochem. 2009 Aug 17;10(12):1959-64. doi: 10.1002/cbic.200900172. Chembiochem. 2009. PMID: 19644994 Free PMC article. No abstract available.

3

Molecular disruption of oncogenic signal transducer and activator of transcription 3 (STAT3) protein.

Fletcher S, Drewry JA, Shahani VM, Page BD, Gunning PT. Fletcher S, et al. Biochem Cell Biol. 2009 Dec;87(6):825-33. doi: 10.1139/o09-044. Biochem Cell Biol. 2009. PMID: 19935868 Review.

4

Signal transducer and activator of transcription 3 inhibitors: a patent review.

Page BD, Ball DP, Gunning PT. Page BD, et al. Expert Opin Ther Pat. 2011 Jan;21(1):65-83. doi: 10.1517/13543776.2011.539205. Epub 2010 Nov 29. Expert Opin Ther Pat. 2011. PMID: 21114420 Review.

5

Antagonism of the Stat3-Stat3 protein dimer with salicylic acid based small molecules.

Fletcher S, Page BD, Zhang X, Yue P, Li ZH, Sharmeen S, Singh J, Zhao W, Schimmer AD, Trudel S, Turkson J, Gunning PT. Fletcher S, et al. ChemMedChem. 2011 Aug 1;6(8):1459-70. doi: 10.1002/cmdc.201100194. Epub 2011 May 25. ChemMedChem. 2011. PMID: 21618433 Free PMC article.

6

Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain.

Page BD, Fletcher S, Yue P, Li Z, Zhang X, Sharmeen S, Datti A, Wrana JL, Trudel S, Schimmer AD, Turkson J, Gunning PT. Page BD, et al. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5605-9. doi: 10.1016/j.bmcl.2011.06.056. Epub 2011 Jun 30. Bioorg Med Chem Lett. 2011. PMID: 21788134 Free PMC article.

7

An activatable multimodal/multifunctional nanoprobe for direct imaging of intracellular drug delivery.

Mitra RN, Doshi M, Zhang X, Tyus JC, Bengtsson N, Fletcher S, Page BD, Turkson J, Gesquiere AJ, Gunning PT, Walter GA, Santra S. Mitra RN, et al. Biomaterials. 2012 Feb;33(5):1500-8. doi: 10.1016/j.biomaterials.2011.10.068. Epub 2011 Nov 10. Biomaterials. 2012. PMID: 22078810 Free PMC article.

8

Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activity.

Page BD, Khoury H, Laister RC, Fletcher S, Vellozo M, Manzoli A, Yue P, Turkson J, Minden MD, Gunning PT. Page BD, et al. J Med Chem. 2012 Feb 9;55(3):1047-55. doi: 10.1021/jm200720n. Epub 2012 Jan 13. J Med Chem. 2012. PMID: 22148584

9

Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts.

Zhang X, Yue P, Page BD, Li T, Zhao W, Namanja AT, Paladino D, Zhao J, Chen Y, Gunning PT, Turkson J. Zhang X, et al. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9623-8. doi: 10.1073/pnas.1121606109. Epub 2012 May 23. Proc Natl Acad Sci U S A. 2012. PMID: 22623533 Free PMC article.

10

Inhibiting aberrant signal transducer and activator of transcription protein activation with tetrapodal, small molecule Src homology 2 domain binders: promising agents against multiple myeloma.

Page BD, Croucher DC, Li ZH, Haftchenary S, Jimenez-Zepeda VH, Atkinson J, Spagnuolo PA, Wong YL, Colaguori R, Lewis AM, Schimmer AD, Trudel S, Gunning PT. Page BD, et al. J Med Chem. 2013 Sep 26;56(18):7190-200. doi: 10.1021/jm3017255. Epub 2013 Sep 13. J Med Chem. 2013. PMID: 23968501

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