Llarrull LI - Search Results

1

Overcoming differences: The catalytic mechanism of metallo-β-lactamases.

Meini MR, Llarrull LI, Vila AJ. Meini MR, et al. Among authors: llarrull li. FEBS Lett. 2015 Nov 14;589(22):3419-32. doi: 10.1016/j.febslet.2015.08.015. Epub 2015 Aug 20. FEBS Lett. 2015. PMID: 26297824 Free PMC article. Review.

2

Asp-120 locates Zn2 for optimal metallo-beta-lactamase activity.

Llarrull LI, Fabiane SM, Kowalski JM, Bennett B, Sutton BJ, Vila AJ. Llarrull LI, et al. J Biol Chem. 2007 Jun 22;282(25):18276-18285. doi: 10.1074/jbc.M700742200. Epub 2007 Apr 10. J Biol Chem. 2007. PMID: 17426028 Free article.

3

Engineered mononuclear variants in Bacillus cereus metallo-beta-lactamase BcII are inactive.

Abriata LA, González LJ, Llarrull LI, Tomatis PE, Myers WK, Costello AL, Tierney DL, Vila AJ. Abriata LA, et al. Among authors: llarrull li. Biochemistry. 2008 Aug 19;47(33):8590-9. doi: 10.1021/bi8006912. Epub 2008 Jul 25. Biochemistry. 2008. PMID: 18652482 Free PMC article.

4

Metal content and localization during turnover in B. cereus metallo-beta-lactamase.

Llarrull LI, Tioni MF, Vila AJ. Llarrull LI, et al. J Am Chem Soc. 2008 Nov 26;130(47):15842-51. doi: 10.1021/ja801168r. J Am Chem Soc. 2008. PMID: 18980306

5

Trapping and characterization of a reaction intermediate in carbapenem hydrolysis by B. cereus metallo-beta-lactamase.

Tioni MF, Llarrull LI, Poeylaut-Palena AA, Martí MA, Saggu M, Periyannan GR, Mata EG, Bennett B, Murgida DH, Vila AJ. Tioni MF, et al. Among authors: llarrull li. J Am Chem Soc. 2008 Nov 26;130(47):15852-63. doi: 10.1021/ja801169j. J Am Chem Soc. 2008. PMID: 18980308 Free PMC article.

6

Evolution of Metallo-β-lactamases: Trends Revealed by Natural Diversity and in vitro Evolution.

Meini MR, Llarrull LI, Vila AJ. Meini MR, et al. Among authors: llarrull li. Antibiotics (Basel). 2014 Jul 1;3(3):285-316. doi: 10.3390/antibiotics3030285. Antibiotics (Basel). 2014. PMID: 25364574 Free PMC article.

7

Exploring the Role of Residue 228 in Substrate and Inhibitor Recognition by VIM Metallo-β-lactamases.

Mojica MF, Mahler SG, Bethel CR, Taracila MA, Kosmopoulou M, Papp-Wallace KM, Llarrull LI, Wilson BM, Marshall SH, Wallace CJ, Villegas MV, Harris ME, Vila AJ, Spencer J, Bonomo RA. Mojica MF, et al. Among authors: llarrull li. Biochemistry. 2015 May 26;54(20):3183-96. doi: 10.1021/acs.biochem.5b00106. Epub 2015 May 12. Biochemistry. 2015. PMID: 25915520 Free PMC article.

8

A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases.

Lisa MN, Palacios AR, Aitha M, González MM, Moreno DM, Crowder MW, Bonomo RA, Spencer J, Tierney DL, Llarrull LI, Vila AJ. Lisa MN, et al. Among authors: llarrull li. Nat Commun. 2017 Sep 14;8(1):538. doi: 10.1038/s41467-017-00601-9. Nat Commun. 2017. PMID: 28912448 Free PMC article.

9

The Reaction Mechanism of Metallo-β-Lactamases Is Tuned by the Conformation of an Active-Site Mobile Loop.

Palacios AR, Mojica MF, Giannini E, Taracila MA, Bethel CR, Alzari PM, Otero LH, Klinke S, Llarrull LI, Bonomo RA, Vila AJ. Palacios AR, et al. Among authors: llarrull li. Antimicrob Agents Chemother. 2018 Dec 21;63(1):e01754-18. doi: 10.1128/AAC.01754-18. Print 2019 Jan. Antimicrob Agents Chemother. 2018. PMID: 30348667 Free PMC article.

10

Water-assisted reaction mechanism of monozinc beta-lactamases.

Dal Peraro M, Llarrull LI, Rothlisberger U, Vila AJ, Carloni P. Dal Peraro M, et al. Among authors: llarrull li. J Am Chem Soc. 2004 Oct 6;126(39):12661-8. doi: 10.1021/ja048071b. J Am Chem Soc. 2004. PMID: 15453800

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