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Targeting the Checkpoint to Kill Cancer Cells.
Benada J, Macurek L. Benada J, et al. Among authors: macurek l. Biomolecules. 2015 Aug 18;5(3):1912-37. doi: 10.3390/biom5031912. Biomolecules. 2015. PMID: 26295265 Free PMC article. Review.
Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint.
Kleiblova P, Shaltiel IA, Benada J, Ševčík J, Pecháčková S, Pohlreich P, Voest EE, Dundr P, Bartek J, Kleibl Z, Medema RH, Macurek L. Kleiblova P, et al. Among authors: macurek l. J Cell Biol. 2013 May 13;201(4):511-21. doi: 10.1083/jcb.201210031. Epub 2013 May 6. J Cell Biol. 2013. PMID: 23649806 Free PMC article.
Residual Cdk1/2 activity after DNA damage promotes senescence.
Müllers E, Silva Cascales H, Burdova K, Macurek L, Lindqvist A. Müllers E, et al. Among authors: macurek l. Aging Cell. 2017 Jun;16(3):575-584. doi: 10.1111/acel.12588. Epub 2017 Mar 26. Aging Cell. 2017. PMID: 28345297 Free PMC article.
WIP1 phosphatase as pharmacological target in cancer therapy.
Pecháčková S, Burdová K, Macurek L. Pecháčková S, et al. Among authors: macurek l. J Mol Med (Berl). 2017 Jun;95(6):589-599. doi: 10.1007/s00109-017-1536-2. Epub 2017 Apr 24. J Mol Med (Berl). 2017. PMID: 28439615 Free PMC article. Review.
Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon.
Burocziova M, Burdova K, Martinikova AS, Kasparek P, Kleiblova P, Danielsen SA, Borecka M, Jenikova G, Janečková L, Pavel J, Zemankova P, Schneiderova M, Schwarzova L, Ticha I, Sun XF, Jiraskova K, Liska V, Vodickova L, Vodicka P, Sedlacek R, Kleibl Z, Lothe RA, Korinek V, Macurek L. Burocziova M, et al. Among authors: macurek l. Cell Death Dis. 2019 Oct 28;10(11):818. doi: 10.1038/s41419-019-2057-4. Cell Death Dis. 2019. PMID: 31659152 Free PMC article.
60 results