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Page 1
Structural insights into the mechanism of protein O-fucosylation.
Lira-Navarrete E, Valero-González J, Villanueva R, Martínez-Júlvez M, Tejero T, Merino P, Panjikar S, Hurtado-Guerrero R. Lira-Navarrete E, et al. Among authors: valero gonzalez j. PLoS One. 2011;6(9):e25365. doi: 10.1371/journal.pone.0025365. Epub 2011 Sep 26. PLoS One. 2011. PMID: 21966509 Free PMC article.
Synthesis of O- and C-glycosides derived from β-(1,3)-D-glucans.
Marca E, Valero-Gonzalez J, Delso I, Tejero T, Hurtado-Guerrero R, Merino P. Marca E, et al. Among authors: valero gonzalez j. Carbohydr Res. 2013 Dec 15;382:9-18. doi: 10.1016/j.carres.2013.07.007. Epub 2013 Jul 30. Carbohydr Res. 2013. PMID: 24140893
Inhibitors against Fungal Cell Wall Remodeling Enzymes.
Delso I, Valero-Gonzalez J, Gomollón-Bel F, Castro-López J, Fang W, Navratilova I, van Aalten DMF, Tejero T, Merino P, Hurtado-Guerrero R. Delso I, et al. Among authors: valero gonzalez j. ChemMedChem. 2018 Jan 22;13(2):128-132. doi: 10.1002/cmdc.201700720. Epub 2017 Dec 12. ChemMedChem. 2018. PMID: 29164827
Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition.
Madariaga D, Martínez-Sáez N, Somovilla VJ, Coelho H, Valero-González J, Castro-López J, Asensio JL, Jiménez-Barbero J, Busto JH, Avenoza A, Marcelo F, Hurtado-Guerrero R, Corzana F, Peregrina JM. Madariaga D, et al. Among authors: valero gonzalez j. ACS Chem Biol. 2015 Mar 20;10(3):747-56. doi: 10.1021/cb500855x. Epub 2014 Dec 10. ACS Chem Biol. 2015. PMID: 25457745
A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2.
Valero-González J, Leonhard-Melief C, Lira-Navarrete E, Jiménez-Osés G, Hernández-Ruiz C, Pallarés MC, Yruela I, Vasudevan D, Lostao A, Corzana F, Takeuchi H, Haltiwanger RS, Hurtado-Guerrero R. Valero-González J, et al. Nat Chem Biol. 2016 Apr;12(4):240-6. doi: 10.1038/nchembio.2019. Epub 2016 Feb 8. Nat Chem Biol. 2016. PMID: 26854667 Free PMC article.
Serine versus threonine glycosylation with α-O-GalNAc: unexpected selectivity in their molecular recognition with lectins.
Madariaga D, Martínez-Sáez N, Somovilla VJ, García-García L, Berbis MÁ, Valero-Gónzalez J, Martín-Santamaría S, Hurtado-Guerrero R, Asensio JL, Jiménez-Barbero J, Avenoza A, Busto JH, Corzana F, Peregrina JM. Madariaga D, et al. Among authors: valero gonzalez j. Chemistry. 2014 Sep 22;20(39):12616-27. doi: 10.1002/chem.201403700. Epub 2014 Aug 8. Chemistry. 2014. PMID: 25111627
Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody.
Martínez-Sáez N, Castro-López J, Valero-González J, Madariaga D, Compañón I, Somovilla VJ, Salvadó M, Asensio JL, Jiménez-Barbero J, Avenoza A, Busto JH, Bernardes GJ, Peregrina JM, Hurtado-Guerrero R, Corzana F. Martínez-Sáez N, et al. Among authors: valero gonzalez j. Angew Chem Int Ed Engl. 2015 Aug 17;54(34):9830-4. doi: 10.1002/anie.201502813. Epub 2015 Jun 26. Angew Chem Int Ed Engl. 2015. PMID: 26118689 Free PMC article.
O-fucosylation stabilizes the TSR3 motif in thrombospondin-1 by interacting with nearby amino acids and protecting a disulfide bond.
Berardinelli SJ, Eletsky A, Valero-González J, Ito A, Manjunath R, Hurtado-Guerrero R, Prestegard JH, Woods RJ, Haltiwanger RS. Berardinelli SJ, et al. Among authors: valero gonzalez j. J Biol Chem. 2022 Jun;298(6):102047. doi: 10.1016/j.jbc.2022.102047. Epub 2022 May 18. J Biol Chem. 2022. PMID: 35597280 Free PMC article.