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CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses.
Hammitzsch A, Tallant C, Fedorov O, O'Mahony A, Brennan PE, Hay DA, Martinez FO, Al-Mossawi MH, de Wit J, Vecellio M, Wells C, Wordsworth P, Müller S, Knapp S, Bowness P. Hammitzsch A, et al. Among authors: de wit j. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10768-73. doi: 10.1073/pnas.1501956112. Epub 2015 Aug 10. Proc Natl Acad Sci U S A. 2015. PMID: 26261308 Free PMC article.
miR-10b-5p is a novel Th17 regulator present in Th17 cells from ankylosing spondylitis.
Chen L, Al-Mossawi MH, Ridley A, Sekine T, Hammitzsch A, de Wit J, Simone D, Shi H, Penkava F, Kurowska-Stolarska M, Pulyakhina I, Knight JC, Kim TJ, Bowness P. Chen L, et al. Among authors: de wit j. Ann Rheum Dis. 2017 Mar;76(3):620-625. doi: 10.1136/annrheumdis-2016-210175. Epub 2016 Dec 30. Ann Rheum Dis. 2017. PMID: 28039186
Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis.
Al-Mossawi MH, Chen L, Fang H, Ridley A, de Wit J, Yager N, Hammitzsch A, Pulyakhina I, Fairfax BP, Simone D, Yi Y, Bandyopadhyay S, Doig K, Gundle R, Kendrick B, Powrie F, Knight JC, Bowness P. Al-Mossawi MH, et al. Among authors: de wit j. Nat Commun. 2017 Nov 15;8(1):1510. doi: 10.1038/s41467-017-01771-2. Nat Commun. 2017. PMID: 29142230 Free PMC article.
RORγt inhibitors suppress T(H)17 responses in inflammatory arthritis and inflammatory bowel disease.
de Wit J, Al-Mossawi MH, Hühn MH, Arancibia-Cárcamo CV, Doig K, Kendrick B, Gundle R, Taylor P, Mcclanahan T, Murphy E, Zhang H, Barr K, Miller JR, Hu X, Aicher TD, Morgan RW, Glick GD, Zaller D, Correll C, Powrie F, Bowness P. de Wit J, et al. J Allergy Clin Immunol. 2016 Mar;137(3):960-3. doi: 10.1016/j.jaci.2015.09.048. Epub 2015 Nov 21. J Allergy Clin Immunol. 2016. PMID: 26611672 No abstract available.
Children and Adults With Mild COVID-19: Dynamics of the Memory T Cell Response up to 10 Months.
Kaaijk P, Pimentel VO, Emmelot ME, Poelen MCM, Cevirgel A, Schepp RM, den Hartog G, Reukers DFM, Beckers L, van Beek J, van Els CACM, Meijer A, Rots NY, de Wit J. Kaaijk P, et al. Among authors: de wit j. Front Immunol. 2022 Feb 7;13:817876. doi: 10.3389/fimmu.2022.817876. eCollection 2022. Front Immunol. 2022. PMID: 35197982 Free PMC article. Clinical Trial.
694 results