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Positive selection in dNTPase SAMHD1 throughout mammalian evolution.
Monit C, Morris ER, Ruis C, Szafran B, Thiltgen G, Tsai MC, Mitchison NA, Bishop KN, Stoye JP, Taylor IA, Fassati A, Goldstein RA. Monit C, et al. Among authors: thiltgen g. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18647-18654. doi: 10.1073/pnas.1908755116. Epub 2019 Aug 26. Proc Natl Acad Sci U S A. 2019. PMID: 31451672 Free PMC article.
Finding Direction in the Search for Selection.
Thiltgen G, Dos Reis M, Goldstein RA. Thiltgen G, et al. J Mol Evol. 2017 Jan;84(1):39-50. doi: 10.1007/s00239-016-9765-5. Epub 2016 Dec 2. J Mol Evol. 2017. PMID: 27913840 Free PMC article.
Gag-Protease Sequence Evolution Following Protease Inhibitor Monotherapy Treatment Failure in HIV-1 Viruses Circulating in East Africa.
Sutherland KA, Goodall RL, McCormick A, Kapaata A, Lyagoba F, Kaleebu P, Thiltgen G, Gilks CF, Spyer M, Kityo C, Pillay D, Dunn D, Gupta RK; DART Virology Group; DART Trial Team. Sutherland KA, et al. Among authors: thiltgen g. AIDS Res Hum Retroviruses. 2015 Oct;31(10):1032-7. doi: 10.1089/aid.2015.0138. Epub 2015 Aug 10. AIDS Res Hum Retroviruses. 2015. PMID: 26258548 Free PMC article.
Amino acid coevolution induces an evolutionary Stokes shift.
Pollock DD, Thiltgen G, Goldstein RA. Pollock DD, et al. Among authors: thiltgen g. Proc Natl Acad Sci U S A. 2012 May 22;109(21):E1352-9. doi: 10.1073/pnas.1120084109. Epub 2012 Apr 30. Proc Natl Acad Sci U S A. 2012. PMID: 22547823 Free PMC article.
PREDICT-2ND: a tool for generalized protein local structure prediction.
Katzman S, Barrett C, Thiltgen G, Karchin R, Karplus K. Katzman S, et al. Among authors: thiltgen g. Bioinformatics. 2008 Nov 1;24(21):2453-9. doi: 10.1093/bioinformatics/btn438. Epub 2008 Aug 30. Bioinformatics. 2008. PMID: 18757875 Free PMC article.