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Exploring the Effect of Conjugation Site and Chemistry on the Immunogenicity of an anti-Group B Streptococcus Glycoconjugate Vaccine Based on GBS67 Pilus Protein and Type V Polysaccharide.
Nilo A, Passalacqua I, Fabbrini M, Allan M, Usera A, Carboni F, Brogioni B, Pezzicoli A, Cobb J, Romano MR, Margarit I, Hu QY, Berti F, Adamo R. Nilo A, et al. Among authors: hu qy. Bioconjug Chem. 2015 Aug 19;26(8):1839-49. doi: 10.1021/acs.bioconjchem.5b00365. Epub 2015 Jul 31. Bioconjug Chem. 2015. PMID: 26230938
Anti-Group B Streptococcus Glycan-Conjugate Vaccines Using Pilus Protein GBS80 As Carrier and Antigen: Comparing Lysine and Tyrosine-directed Conjugation.
Nilo A, Morelli L, Passalacqua I, Brogioni B, Allan M, Carboni F, Pezzicoli A, Zerbini F, Maione D, Fabbrini M, Romano MR, Hu QY, Margarit I, Berti F, Adamo R. Nilo A, et al. Among authors: hu qy. ACS Chem Biol. 2015 Jul 17;10(7):1737-46. doi: 10.1021/acschembio.5b00247. Epub 2015 May 6. ACS Chem Biol. 2015. PMID: 25906283
Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines.
Stefanetti G, Hu QY, Usera A, Robinson Z, Allan M, Singh A, Imase H, Cobb J, Zhai H, Quinn D, Lei M, Saul A, Adamo R, MacLennan CA, Micoli F. Stefanetti G, et al. Among authors: hu qy. Angew Chem Int Ed Engl. 2015 Nov 2;54(45):13198-203. doi: 10.1002/anie.201506112. Epub 2015 Sep 9. Angew Chem Int Ed Engl. 2015. PMID: 26350581 Free PMC article.
Correction to Exploring the Effect of Conjugation Site and Chemistry on the Immunogenicity of an anti-Group B Streptococcus Glycoconjugate Vaccine Based on GBS67 Pilus Protein and Type V Polysaccharide.
Nilo A, Passalacqua I, Fabbrini M, Allan M, Usera A, Carboni F, Brogioni B, Pezzicoli A, Cobb J, Romano MR, Margarit I, Hu QY, Berti F, Adamo R. Nilo A, et al. Among authors: hu qy. Bioconjug Chem. 2015 Oct 21;26(10):2167. doi: 10.1021/acs.bioconjchem.5b00480. Epub 2015 Sep 10. Bioconjug Chem. 2015. PMID: 26355285 No abstract available.
Structure-Activity Relationships, Pharmacokinetics, and in Vivo Activity of CYP11B2 and CYP11B1 Inhibitors.
Papillon JP, Adams CM, Hu QY, Lou C, Singh AK, Zhang C, Carvalho J, Rajan S, Amaral A, Beil ME, Fu F, Gangl E, Hu CW, Jeng AY, LaSala D, Liang G, Logman M, Maniara WM, Rigel DF, Smith SA, Ksander GM. Papillon JP, et al. Among authors: hu qy, hu cw. J Med Chem. 2015 Jun 11;58(11):4749-70. doi: 10.1021/acs.jmedchem.5b00407. Epub 2015 May 21. J Med Chem. 2015. PMID: 25953419
Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors.
Meredith EL, Ksander G, Monovich LG, Papillon JP, Liu Q, Miranda K, Morris P, Rao C, Burgis R, Capparelli M, Hu QY, Singh A, Rigel DF, Jeng AY, Beil M, Fu F, Hu CW, LaSala D. Meredith EL, et al. Among authors: hu qy, hu cw. ACS Med Chem Lett. 2013 Oct 17;4(12):1203-7. doi: 10.1021/ml400324c. eCollection 2013 Dec 12. ACS Med Chem Lett. 2013. PMID: 24900631 Free PMC article.
Implications of Dynamic Occupancy, Binding Kinetics, and Channel Gating Kinetics for hERG Blocker Safety Assessment and Mitigation.
Pearlstein RA, MacCannell KA, Erdemli G, Yeola S, Helmlinger G, Hu QY, Farid R, Egan W, Whitebread S, Springer C, Beck J, Wang HR, Maciejewski M, Urban L, Duca JS. Pearlstein RA, et al. Among authors: hu qy. Curr Top Med Chem. 2016;16(16):1792-818. doi: 10.2174/1568026616666160315142156. Curr Top Med Chem. 2016. PMID: 26975508 Review.
168 results