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A Ligand-Based Drug Design. Discovery of 4-Trifluoromethyl-7,8-pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2.
Liu J, Pham PT, Skripnikova EV, Zheng S, Lovings LJ, Wang Y, Goyal N, Bellow SM, Mensah LM, Chatters AJ, Bratton MR, Wiese TE, Zhao M, Wang G, Foroozesh M. Liu J, et al. Among authors: wiese te. J Med Chem. 2015 Aug 27;58(16):6481-93. doi: 10.1021/acs.jmedchem.5b00494. Epub 2015 Aug 10. J Med Chem. 2015. PMID: 26222195 Free PMC article.
Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells.
Jiang Q, Payton-Stewart F, Elliott S, Driver J, Rhodes LV, Zhang Q, Zheng S, Bhatnagar D, Boue SM, Collins-Burow BM, Sridhar J, Stevens C, McLachlan JA, Wiese TE, Burow ME, Wang G. Jiang Q, et al. Among authors: wiese te. J Med Chem. 2010 Aug 26;53(16):6153-63. doi: 10.1021/jm100610w. J Med Chem. 2010. PMID: 20669983 Free PMC article.
Sequence and functional characterization of hypoxia-inducible factors, HIF1α, HIF2αa, and HIF3α, from the estuarine fish, Fundulus heteroclitus.
Townley IK, Karchner SI, Skripnikova E, Wiese TE, Hahn ME, Rees BB. Townley IK, et al. Among authors: wiese te. Am J Physiol Regul Integr Comp Physiol. 2017 Mar 1;312(3):R412-R425. doi: 10.1152/ajpregu.00402.2016. Epub 2016 Dec 30. Am J Physiol Regul Integr Comp Physiol. 2017. PMID: 28039194 Free PMC article.
ZB716, a steroidal selective estrogen receptor degrader (SERD), is orally efficacious in blocking tumor growth in mouse xenograft models.
Guo S, Zhang C, Bratton M, Mottamal M, Liu J, Ma P, Zheng S, Zhong Q, Yang L, Wiese TE, Wu Y, Ellis MJ, Matossian M, Burow ME, Miele L, Houtman R, Wang G. Guo S, et al. Among authors: wiese te. Oncotarget. 2018 Jan 8;9(6):6924-6937. doi: 10.18632/oncotarget.24023. eCollection 2018 Jan 23. Oncotarget. 2018. PMID: 29467940 Free PMC article.
39 results