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A Ligand-Based Drug Design. Discovery of 4-Trifluoromethyl-7,8-pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2.
Liu J, Pham PT, Skripnikova EV, Zheng S, Lovings LJ, Wang Y, Goyal N, Bellow SM, Mensah LM, Chatters AJ, Bratton MR, Wiese TE, Zhao M, Wang G, Foroozesh M. Liu J, et al. Among authors: wang g, wang y. J Med Chem. 2015 Aug 27;58(16):6481-93. doi: 10.1021/acs.jmedchem.5b00494. Epub 2015 Aug 10. J Med Chem. 2015. PMID: 26222195 Free PMC article.
Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype.
Zhou C, Nitschke AM, Xiong W, Zhang Q, Tang Y, Bloch M, Elliott S, Zhu Y, Bazzone L, Yu D, Weldon CB, Schiff R, McLachlan JA, Beckman BS, Wiese TE, Nephew KP, Shan B, Burow ME, Wang G. Zhou C, et al. Among authors: wang g. Breast Cancer Res. 2008;10(6):R105. doi: 10.1186/bcr2210. Epub 2008 Dec 16. Breast Cancer Res. 2008. PMID: 19087274 Free PMC article.
Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells.
Jiang Q, Payton-Stewart F, Elliott S, Driver J, Rhodes LV, Zhang Q, Zheng S, Bhatnagar D, Boue SM, Collins-Burow BM, Sridhar J, Stevens C, McLachlan JA, Wiese TE, Burow ME, Wang G. Jiang Q, et al. Among authors: wang g. J Med Chem. 2010 Aug 26;53(16):6153-63. doi: 10.1021/jm100610w. J Med Chem. 2010. PMID: 20669983 Free PMC article.
Proteomic signatures of acquired letrozole resistance in breast cancer: suppressed estrogen signaling and increased cell motility and invasiveness.
Tilghman SL, Townley I, Zhong Q, Carriere PP, Zou J, Llopis SD, Preyan LC, Williams CC, Skripnikova E, Bratton MR, Zhang Q, Wang G. Tilghman SL, et al. Among authors: wang g. Mol Cell Proteomics. 2013 Sep;12(9):2440-55. doi: 10.1074/mcp.M112.023861. Epub 2013 May 23. Mol Cell Proteomics. 2013. PMID: 23704778 Free PMC article.
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