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A liquid crystal of ascorbyl palmitate, used as vaccine platform, provides sustained release of antigen and has intrinsic pro-inflammatory and adjuvant activities which are dependent on MyD88 adaptor protein.
Sánchez Vallecillo MF, Minguito de la Escalera MM, Aguirre MV, Ullio Gamboa GV, Palma SD, González-Cintado L, Chiodetti AL, Soldano G, Morón G, Allemandi DA, Ardavín C, Pistoresi-Palencia MC, Maletto BA. Sánchez Vallecillo MF, et al. Among authors: ardavin c. J Control Release. 2015 Sep 28;214:12-22. doi: 10.1016/j.jconrel.2015.07.008. Epub 2015 Jul 15. J Control Release. 2015. PMID: 26188153
IL-4 blocks TH1-polarizing/inflammatory cytokine gene expression during monocyte-derived dendritic cell differentiation through histone hypoacetylation.
López-Bravo M, Minguito de la Escalera M, Domínguez PM, González-Cintado L, del Fresno C, Martín P, Martínez del Hoyo G, Ardavín C. López-Bravo M, et al. Among authors: ardavin c. J Allergy Clin Immunol. 2013 Dec;132(6):1409-19. doi: 10.1016/j.jaci.2013.08.039. Epub 2013 Oct 17. J Allergy Clin Immunol. 2013. PMID: 24139608
CD81 controls immunity to Listeria infection through rac-dependent inhibition of proinflammatory mediator release and activation of cytotoxic T cells.
Martínez del Hoyo G, Ramírez-Huesca M, Levy S, Boucheix C, Rubinstein E, Minguito de la Escalera M, González-Cintado L, Ardavín C, Veiga E, Yáñez-Mó M, Sánchez-Madrid F. Martínez del Hoyo G, et al. Among authors: ardavin c. J Immunol. 2015 Jun 15;194(12):6090-101. doi: 10.4049/jimmunol.1402957. Epub 2015 May 13. J Immunol. 2015. PMID: 25972472
Chimeric infectious bursal disease virus-like particles as potent vaccines for eradication of established HPV-16 E7-dependent tumors.
Martin Caballero J, Garzón A, González-Cintado L, Kowalczyk W, Jimenez Torres I, Calderita G, Rodriguez M, Gondar V, Bernal JJ, Ardavín C, Andreu D, Zürcher T, von Kobbe C. Martin Caballero J, et al. Among authors: ardavin c. PLoS One. 2012;7(12):e52976. doi: 10.1371/journal.pone.0052976. Epub 2012 Dec 31. PLoS One. 2012. PMID: 23300838 Free PMC article.
Resident macrophage-dependent immune cell scaffolds drive anti-bacterial defense in the peritoneal cavity.
Vega-Pérez A, Villarrubia LH, Godio C, Gutiérrez-González A, Feo-Lucas L, Ferriz M, Martínez-Puente N, Alcaín J, Mora A, Sabio G, López-Bravo M, Ardavín C. Vega-Pérez A, et al. Among authors: ardavin c. Immunity. 2021 Nov 9;54(11):2578-2594.e5. doi: 10.1016/j.immuni.2021.10.007. Epub 2021 Oct 29. Immunity. 2021. PMID: 34717795 Free article.
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