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Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma.
Agelopoulos K, Richter GH, Schmidt E, Dirksen U, von Heyking K, Moser B, Klein HU, Kontny U, Dugas M, Poos K, Korsching E, Buch T, Weckesser M, Schulze I, Besoke R, Witten A, Stoll M, Köhler G, Hartmann W, Wardelmann E, Rossig C, Baumhoer D, Jürgens H, Burdach S, Berdel WE, Müller-Tidow C. Agelopoulos K, et al. Among authors: baumhoer d. Clin Cancer Res. 2015 Nov 1;21(21):4935-46. doi: 10.1158/1078-0432.CCR-14-2744. Epub 2015 Jul 15. Clin Cancer Res. 2015. PMID: 26179511 Free article.
Genomic alterations and allelic imbalances are strong prognostic predictors in osteosarcoma.
Smida J, Baumhoer D, Rosemann M, Walch A, Bielack S, Poremba C, Remberger K, Korsching E, Scheurlen W, Dierkes C, Burdach S, Jundt G, Atkinson MJ, Nathrath M. Smida J, et al. Among authors: baumhoer d. Clin Cancer Res. 2010 Aug 15;16(16):4256-67. doi: 10.1158/1078-0432.CCR-10-0284. Epub 2010 Jul 7. Clin Cancer Res. 2010. PMID: 20610556 Free article.
High STEAP1 expression is associated with improved outcome of Ewing's sarcoma patients.
Grunewald TGP, Ranft A, Esposito I, da Silva-Buttkus P, Aichler M, Baumhoer D, Schaefer KL, Ottaviano L, Poremba C, Jundt G, Jürgens H, Dirksen U, Richter GHS, Burdach S. Grunewald TGP, et al. Among authors: baumhoer d. Ann Oncol. 2012 Aug;23(8):2185-2190. doi: 10.1093/annonc/mdr605. Epub 2012 Feb 8. Ann Oncol. 2012. PMID: 22317770 Free article.
DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma.
Hauer K, Calzada-Wack J, Steiger K, Grunewald TG, Baumhoer D, Plehm S, Buch T, Prazeres da Costa O, Esposito I, Burdach S, Richter GH. Hauer K, et al. Among authors: baumhoer d. Cancer Res. 2013 Jan 15;73(2):967-77. doi: 10.1158/0008-5472.CAN-12-1492. Epub 2012 Nov 30. Cancer Res. 2013. PMID: 23204234
New small molecules targeting apoptosis and cell viability in osteosarcoma.
Maugg D, Rothenaigner I, Schorpp K, Potukuchi HK, Korsching E, Baumhoer D, Hadian K, Smida J, Nathrath M. Maugg D, et al. Among authors: baumhoer d. PLoS One. 2015 Jun 3;10(6):e0129058. doi: 10.1371/journal.pone.0129058. eCollection 2015. PLoS One. 2015. PMID: 26039064 Free PMC article.
Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency.
Kovac M, Blattmann C, Ribi S, Smida J, Mueller NS, Engert F, Castro-Giner F, Weischenfeldt J, Kovacova M, Krieg A, Andreou D, Tunn PU, Dürr HR, Rechl H, Schaser KD, Melcher I, Burdach S, Kulozik A, Specht K, Heinimann K, Fulda S, Bielack S, Jundt G, Tomlinson I, Korbel JO, Nathrath M, Baumhoer D. Kovac M, et al. Among authors: baumhoer d. Nat Commun. 2015 Dec 3;6:8940. doi: 10.1038/ncomms9940. Nat Commun. 2015. PMID: 26632267 Free PMC article.
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