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Langerhans cells in innate defense against pathogens.
de Jong MA, Geijtenbeek TB. de Jong MA, et al. Trends Immunol. 2010 Dec;31(12):452-9. doi: 10.1016/j.it.2010.08.002. Epub 2010 Oct 26. Trends Immunol. 2010. PMID: 21030306 Review.
Human Langerhans cells capture measles virus through Langerin and present viral antigens to CD4⁺ T cells but are incapable of cross-presentation.
van der Vlist M, de Witte L, de Vries RD, Litjens M, de Jong MA, Fluitsma D, de Swart RL, Geijtenbeek TB. van der Vlist M, et al. Among authors: de witte l, de swart rl, de jong ma, de vries rd. Eur J Immunol. 2011 Sep;41(9):2619-31. doi: 10.1002/eji.201041305. Epub 2011 Aug 8. Eur J Immunol. 2011. PMID: 21739428 Free article.
Langerin is a natural barrier to HIV-1 transmission by Langerhans cells.
de Witte L, Nabatov A, Pion M, Fluitsma D, de Jong MA, de Gruijl T, Piguet V, van Kooyk Y, Geijtenbeek TB. de Witte L, et al. Among authors: de jong ma, de gruijl t. Nat Med. 2007 Mar;13(3):367-71. doi: 10.1038/nm1541. Epub 2007 Mar 4. Nat Med. 2007. PMID: 17334373
135 results