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Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis.
Axelsen LN, Calloe K, Braunstein TH, Riemann M, Hofgaard JP, Liang B, Jensen CF, Olsen KB, Bartels ED, Baandrup U, Jespersen T, Nielsen LB, Holstein-Rathlou NH, Nielsen MS. Axelsen LN, et al. Among authors: baandrup u. Cardiovasc Diabetol. 2015 Jul 14;14:87. doi: 10.1186/s12933-015-0246-8. Cardiovasc Diabetol. 2015. PMID: 26169175 Free PMC article.
Truncating plakophilin-2 mutations in arrhythmogenic cardiomyopathy are associated with protein haploinsufficiency in both myocardium and epidermis.
Rasmussen TB, Nissen PH, Palmfeldt J, Gehmlich K, Dalager S, Jensen UB, Kim WY, Heickendorff L, Mølgaard H, Jensen HK, Baandrup UT, Bross P, Mogensen J. Rasmussen TB, et al. Circ Cardiovasc Genet. 2014 Jun;7(3):230-40. doi: 10.1161/CIRCGENETICS.113.000338. Epub 2014 Apr 4. Circ Cardiovasc Genet. 2014. PMID: 24704780
The thick left ventricular wall of the giraffe heart normalises wall tension, but limits stroke volume and cardiac output.
Smerup M, Damkjær M, Brøndum E, Baandrup UT, Kristiansen SB, Nygaard H, Funder J, Aalkjær C, Sauer C, Buchanan R, Bertelsen MF, Østergaard K, Grøndahl C, Candy G, Hasenkam JM, Secher NH, Bie P, Wang T. Smerup M, et al. J Exp Biol. 2016 Feb;219(Pt 3):457-63. doi: 10.1242/jeb.132753. Epub 2015 Dec 7. J Exp Biol. 2016. PMID: 26643090
167 results