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H3K36 methylation promotes longevity by enhancing transcriptional fidelity.
Sen P, Dang W, Donahue G, Dai J, Dorsey J, Cao X, Liu W, Cao K, Perry R, Lee JY, Wasko BM, Carr DT, He C, Robison B, Wagner J, Gregory BD, Kaeberlein M, Kennedy BK, Boeke JD, Berger SL. Sen P, et al. Among authors: berger sl. Genes Dev. 2015 Jul 1;29(13):1362-76. doi: 10.1101/gad.263707.115. Genes Dev. 2015. PMID: 26159996 Free PMC article.
Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications.
Nathan D, Ingvarsdottir K, Sterner DE, Bylebyl GR, Dokmanovic M, Dorsey JA, Whelan KA, Krsmanovic M, Lane WS, Meluh PB, Johnson ES, Berger SL. Nathan D, et al. Among authors: berger sl. Genes Dev. 2006 Apr 15;20(8):966-76. doi: 10.1101/gad.1404206. Epub 2006 Apr 5. Genes Dev. 2006. PMID: 16598039 Free PMC article.
Repression of p53 activity by Smyd2-mediated methylation.
Huang J, Perez-Burgos L, Placek BJ, Sengupta R, Richter M, Dorsey JA, Kubicek S, Opravil S, Jenuwein T, Berger SL. Huang J, et al. Among authors: berger sl. Nature. 2006 Nov 30;444(7119):629-32. doi: 10.1038/nature05287. Epub 2006 Nov 15. Nature. 2006. PMID: 17108971
p53 is regulated by the lysine demethylase LSD1.
Huang J, Sengupta R, Espejo AB, Lee MG, Dorsey JA, Richter M, Opravil S, Shiekhattar R, Bedford MT, Jenuwein T, Berger SL. Huang J, et al. Among authors: berger sl. Nature. 2007 Sep 6;449(7158):105-8. doi: 10.1038/nature06092. Nature. 2007. PMID: 17805299
The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.
Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, Hublarova P, Moyal L, Gana-Weisz M, Shiloh Y, Yarden Y, Johnsen SA, Vojtesek B, Berger SL, Oren M. Shema E, et al. Among authors: berger sl. Genes Dev. 2008 Oct 1;22(19):2664-76. doi: 10.1101/gad.1703008. Genes Dev. 2008. PMID: 18832071 Free PMC article.
311 results