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A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly.
Abdulkarim B, Nicolino M, Igoillo-Esteve M, Daures M, Romero S, Philippi A, Senée V, Lopes M, Cunha DA, Harding HP, Derbois C, Bendelac N, Hattersley AT, Eizirik DL, Ron D, Cnop M, Julier C. Abdulkarim B, et al. Among authors: cunha da. Diabetes. 2015 Nov;64(11):3951-62. doi: 10.2337/db15-0477. Epub 2015 Jul 9. Diabetes. 2015. PMID: 26159176 Free PMC article.
Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.
Cunha DA, Igoillo-Esteve M, Gurzov EN, Germano CM, Naamane N, Marhfour I, Fukaya M, Vanderwinden JM, Gysemans C, Mathieu C, Marselli L, Marchetti P, Harding HP, Ron D, Eizirik DL, Cnop M. Cunha DA, et al. Diabetes. 2012 Nov;61(11):2763-75. doi: 10.2337/db12-0123. Epub 2012 Jul 6. Diabetes. 2012. PMID: 22773666 Free PMC article.
RNA sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate.
Cnop M, Abdulkarim B, Bottu G, Cunha DA, Igoillo-Esteve M, Masini M, Turatsinze JV, Griebel T, Villate O, Santin I, Bugliani M, Ladriere L, Marselli L, McCarthy MI, Marchetti P, Sammeth M, Eizirik DL. Cnop M, et al. Among authors: cunha da. Diabetes. 2014 Jun;63(6):1978-93. doi: 10.2337/db13-1383. Epub 2013 Dec 30. Diabetes. 2014. PMID: 24379348
JunB protects β-cells from lipotoxicity via the XBP1-AKT pathway.
Cunha DA, Gurzov EN, Naamane N, Ortis F, Cardozo AK, Bugliani M, Marchetti P, Eizirik DL, Cnop M. Cunha DA, et al. Cell Death Differ. 2014 Aug;21(8):1313-24. doi: 10.1038/cdd.2014.53. Epub 2014 May 2. Cell Death Differ. 2014. PMID: 24786832 Free PMC article.
106 results