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Synthesis of Biologically Active Piperidine Metabolites of Clopidogrel: Determination of Structure and Analyte Development.
Shaw SA, Balasubramanian B, Bonacorsi S, Cortes JC, Cao K, Chen BC, Dai J, Decicco C, Goswami A, Guo Z, Hanson R, Humphreys WG, Lam PY, Li W, Mathur A, Maxwell BD, Michaudel Q, Peng L, Pudzianowski A, Qiu F, Su S, Sun D, Tymiak AA, Vokits BP, Wang B, Wexler R, Wu DR, Zhang Y, Zhao R, Baran PS. Shaw SA, et al. Among authors: guo z. J Org Chem. 2015 Jul 17;80(14):7019-32. doi: 10.1021/acs.joc.5b00632. Epub 2015 Jul 7. J Org Chem. 2015. PMID: 26151079
Correction to "Synthesis of Biologically Active Piperidine Metabolites of Clopidogrel: Determination of Structure and Analyte Development".
Shaw SA, Balasubramanian B, Bonacorsi S, Caceres Cortes J, Cao K, Chen BC, Dai J, Decicco C, Goswami A, Guo Z, Hanson R, Humphreys WG, Lam PY, Li W, Mathur A, Maxwell BD, Michaudel Q, Peng L, Pudzianowski A, Qiu F, Su S, Sun D, Tymiak AA, Vokits BP, Wang B, Wexler R, Wu DR, Zhang Y, Zhao R, Baran PS. Shaw SA, et al. Among authors: guo z. J Org Chem. 2015 Sep 18;80(18):9370. doi: 10.1021/acs.joc.5b02011. Epub 2015 Sep 2. J Org Chem. 2015. PMID: 26332153 No abstract available.
Improving physical properties via C-H oxidation: chemical and enzymatic approaches.
Michaudel Q, Journot G, Regueiro-Ren A, Goswami A, Guo Z, Tully TP, Zou L, Ramabhadran RO, Houk KN, Baran PS. Michaudel Q, et al. Among authors: guo z. Angew Chem Int Ed Engl. 2014 Nov 3;53(45):12091-6. doi: 10.1002/anie.201407016. Epub 2014 Sep 22. Angew Chem Int Ed Engl. 2014. PMID: 25244630 Free PMC article.
Efficient and scalable enantioselective synthesis of a CGRP antagonist.
Leahy DK, Fan Y, Desai LV, Chan C, Zhu J, Luo G, Chen L, Hanson RL, Sugiyama M, Rosner T, Cuniere N, Guo Z, Hsiao Y, Gao Q. Leahy DK, et al. Among authors: guo z. Org Lett. 2012 Sep 21;14(18):4938-41. doi: 10.1021/ol302262q. Epub 2012 Sep 6. Org Lett. 2012. PMID: 22954228
Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3'-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor.
Ye XY, Chen SY, Wu S, Yoon DS, Wang H, Hong Z, O'Connor SP, Li J, Li JJ, Kennedy LJ, Walker SJ, Nayeem A, Sheriff S, Camac DM, Ramamurthy V, Morin PE, Zebo R, Taylor JR, Morgan NN, Ponticiello RP, Harrity T, Apedo A, Golla R, Seethala R, Wang M, Harper TW, Sleczka BG, He B, Kirby M, Leahy DK, Li J, Hanson RL, Guo Z, Li YX, DiMarco JD, Scaringe R, Maxwell B, Moulin F, Barrish JC, Gordon DA, Robl JA. Ye XY, et al. Among authors: guo z. J Med Chem. 2017 Jun 22;60(12):4932-4948. doi: 10.1021/acs.jmedchem.7b00211. Epub 2017 Jun 5. J Med Chem. 2017. PMID: 28537398
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