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1,8-Naphthalimide derivatives: new leads against dynamin I GTPase activity.
Abdel-Hamid MK, Macgregor KA, Odell LR, Chau N, Mariana A, Whiting A, Robinson PJ, McCluskey A. Abdel-Hamid MK, et al. Among authors: whiting a. Org Biomol Chem. 2015 Aug 7;13(29):8016-28. doi: 10.1039/c5ob00751h. Epub 2015 Jun 29. Org Biomol Chem. 2015. PMID: 26118967
Development of second-generation indole-based dynamin GTPase inhibitors.
Gordon CP, Venn-Brown B, Robertson MJ, Young KA, Chau N, Mariana A, Whiting A, Chircop M, Robinson PJ, McCluskey A. Gordon CP, et al. Among authors: whiting a. J Med Chem. 2013 Jan 10;56(1):46-59. doi: 10.1021/jm300844m. Epub 2012 Dec 18. J Med Chem. 2013. PMID: 23167654
Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors.
McGeachie AB, Odell LR, Quan A, Daniel JA, Chau N, Hill TA, Gorgani NN, Keating DJ, Cousin MA, van Dam EM, Mariana A, Whiting A, Perera S, Novelle A, Young KA, Deane FM, Gilbert J, Sakoff JA, Chircop M, McCluskey A, Robinson PJ. McGeachie AB, et al. Among authors: whiting a. ACS Chem Biol. 2013 Jul 19;8(7):1507-18. doi: 10.1021/cb400137p. Epub 2013 May 30. ACS Chem Biol. 2013. PMID: 23642287
Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis.
McCluskey A, Daniel JA, Hadzic G, Chau N, Clayton EL, Mariana A, Whiting A, Gorgani NN, Lloyd J, Quan A, Moshkanbaryans L, Krishnan S, Perera S, Chircop M, von Kleist L, McGeachie AB, Howes MT, Parton RG, Campbell M, Sakoff JA, Wang X, Sun JY, Robertson MJ, Deane FM, Nguyen TH, Meunier FA, Cousin MA, Robinson PJ. McCluskey A, et al. Among authors: whiting a. Traffic. 2013 Dec;14(12):1272-89. doi: 10.1111/tra.12119. Epub 2013 Oct 9. Traffic. 2013. PMID: 24025110 Free PMC article.
Development of 1,8-naphthalimides as clathrin inhibitors.
MacGregor KA, Robertson MJ, Young KA, von Kleist L, Stahlschmidt W, Whiting A, Chau N, Robinson PJ, Haucke V, McCluskey A. MacGregor KA, et al. Among authors: whiting a. J Med Chem. 2014 Jan 9;57(1):131-43. doi: 10.1021/jm4015263. Epub 2013 Dec 18. J Med Chem. 2014. PMID: 24299503
The Rhodadyns, a New Class of Small Molecule Inhibitors of Dynamin GTPase Activity.
Robertson MJ, Hadzic G, Ambrus J, Pomè DY, Hyde E, Whiting A, Mariana A, von Kleist L, Chau N, Haucke V, Robinson PJ, McCluskey A. Robertson MJ, et al. Among authors: whiting a. ACS Med Chem Lett. 2012 Mar 26;3(5):352-6. doi: 10.1021/ml200284s. eCollection 2012 May 10. ACS Med Chem Lett. 2012. PMID: 24900478 Free PMC article.
Development of quinone analogues as dynamin GTPase inhibitors.
MacGregor KA, Abdel-Hamid MK, Odell LR, Chau N, Whiting A, Robinson PJ, McCluskey A. MacGregor KA, et al. Among authors: whiting a. Eur J Med Chem. 2014 Oct 6;85:191-206. doi: 10.1016/j.ejmech.2014.06.070. Epub 2014 Jul 5. Eur J Med Chem. 2014. PMID: 25084145
5-Aryl-2-(naphtha-1-yl)sulfonamido-thiazol-4(5H)-ones as clathrin inhibitors.
Robertson MJ, Horatscheck A, Sauer S, von Kleist L, Baker JR, Stahlschmidt W, Nazaré M, Whiting A, Chau N, Robinson PJ, Haucke V, McCluskey A. Robertson MJ, et al. Among authors: whiting a. Org Biomol Chem. 2016 Nov 29;14(47):11266-11278. doi: 10.1039/c6ob02308h. Org Biomol Chem. 2016. PMID: 27853797
295 results