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Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs.
PLoS One. 2015 Jun 24;10(6):e0131241. doi: 10.1371/journal.pone.0131241. eCollection 2015.
PLoS One. 2015.
PMID: 26107737
Free PMC article.
New synthetic inhibitors of fatty acid synthase with anticancer activity.
Turrado C, Puig T, García-Cárceles J, Artola M, Benhamú B, Ortega-Gutiérrez S, Relat J, Oliveras G, Blancafort A, Haro D, Marrero PF, Colomer R, López-Rodríguez ML.
Turrado C, et al. Among authors: blancafort a.
J Med Chem. 2012 Jun 14;55(11):5013-23. doi: 10.1021/jm2016045. Epub 2012 May 16.
J Med Chem. 2012.
PMID: 22559865
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Preclinical Evaluation of Fatty Acid Synthase and EGFR Inhibition in Triple-Negative Breast Cancer.
Giró-Perafita A, Palomeras S, Lum DH, Blancafort A, Viñas G, Oliveras G, Pérez-Bueno F, Sarrats A, Welm AL, Puig T.
Giró-Perafita A, et al. Among authors: blancafort a.
Clin Cancer Res. 2016 Sep 15;22(18):4687-97. doi: 10.1158/1078-0432.CCR-15-3133. Epub 2016 Apr 22.
Clin Cancer Res. 2016.
PMID: 27106068
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Novel anti-fatty acid synthase compounds with anti-cancer activity in HER2+ breast cancer.
Oliveras G, Blancafort A, Urruticoechea A, Campuzano O, Gómez-Cabello D, Brugada R, López-Rodríguez ML, Colomer R, Puig T.
Oliveras G, et al. Among authors: blancafort a.
Ann N Y Acad Sci. 2010 Oct;1210:86-92. doi: 10.1111/j.1749-6632.2010.05777.x.
Ann N Y Acad Sci. 2010.
PMID: 20973802
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Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer.
Relat J, Blancafort A, Oliveras G, Cufí S, Haro D, Marrero PF, Puig T.
Relat J, et al. Among authors: blancafort a.
BMC Cancer. 2012 Jul 6;12:280. doi: 10.1186/1471-2407-12-280.
BMC Cancer. 2012.
PMID: 22769244
Free PMC article.
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Fatty acid synthase expression is strongly related to menopause in early-stage breast cancer patients.
Porta R, Blancafort A, Casòliva G, Casas M, Dorca J, Buxo M, Viñas G, Oliveras G, Puig T.
Porta R, et al. Among authors: blancafort a.
Menopause. 2014 Feb;21(2):188-91. doi: 10.1097/GME.0b013e31829d17dc.
Menopause. 2014.
PMID: 23982110
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