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The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ß1-42 oligomers in mice.
Leggio GM, Catania MV, Puzzo D, Spatuzza M, Pellitteri R, Gulisano W, Torrisi SA, Giurdanella G, Piazza C, Impellizzeri AR, Gozzo L, Navarria A, Bucolo C, Nicoletti F, Palmeri A, Salomone S, Copani A, Caraci F, Drago F. Leggio GM, et al. Among authors: drago f. Pharmacol Res. 2016 Apr;106:10-20. doi: 10.1016/j.phrs.2016.02.007. Epub 2016 Feb 10. Pharmacol Res. 2016. PMID: 26875816
Neurobiological links between depression and AD: The role of TGF-β1 signaling as a new pharmacological target.
Caraci F, Spampinato SF, Morgese MG, Tascedda F, Salluzzo MG, Giambirtone MC, Caruso G, Munafò A, Torrisi SA, Leggio GM, Trabace L, Nicoletti F, Drago F, Sortino MA, Copani A. Caraci F, et al. Among authors: drago f. Pharmacol Res. 2018 Apr;130:374-384. doi: 10.1016/j.phrs.2018.02.007. Epub 2018 Feb 10. Pharmacol Res. 2018. PMID: 29438781 Review.
Fluoxetine and Vortioxetine Reverse Depressive-Like Phenotype and Memory Deficits Induced by Aβ1-42 Oligomers in Mice: A Key Role of Transforming Growth Factor-β1.
Torrisi SA, Geraci F, Tropea MR, Grasso M, Caruso G, Fidilio A, Musso N, Sanfilippo G, Tascedda F, Palmeri A, Salomone S, Drago F, Puzzo D, Leggio GM, Caraci F. Torrisi SA, et al. Among authors: drago f. Front Pharmacol. 2019 Jun 21;10:693. doi: 10.3389/fphar.2019.00693. eCollection 2019. Front Pharmacol. 2019. PMID: 31293421 Free PMC article.
TGF-β1 pathway as a new target for neuroprotection in Alzheimer's disease.
Caraci F, Battaglia G, Bruno V, Bosco P, Carbonaro V, Giuffrida ML, Drago F, Sortino MA, Nicoletti F, Copani A. Caraci F, et al. Among authors: drago f. CNS Neurosci Ther. 2011 Aug;17(4):237-49. doi: 10.1111/j.1755-5949.2009.00115.x. Epub 2009 Nov 19. CNS Neurosci Ther. 2011. PMID: 19925479 Free PMC article. Review.
TGF-β1 prevents rat retinal insult induced by amyloid-β (1-42) oligomers.
Fisichella V, Giurdanella G, Platania CB, Romano GL, Leggio GM, Salomone S, Drago F, Caraci F, Bucolo C. Fisichella V, et al. Among authors: drago f. Eur J Pharmacol. 2016 Sep 15;787:72-7. doi: 10.1016/j.ejphar.2016.02.002. Epub 2016 Feb 2. Eur J Pharmacol. 2016. PMID: 26845696
1,115 results