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A genome-wide association study of late-onset Alzheimer's disease in a Japanese population.
Hirano A, Ohara T, Takahashi A, Aoki M, Fuyuno Y, Ashikawa K, Morihara T, Takeda M, Kamino K, Oshima E, Okahisa Y, Shibata N, Arai H, Akatsu H, Ikeda M, Iwata N, Ninomiya T, Monji A, Kitazono T, Kiyohara Y, Kubo M, Kanba S. Hirano A, et al. Psychiatr Genet. 2015 Aug;25(4):139-46. doi: 10.1097/YPG.0000000000000090. Psychiatr Genet. 2015. PMID: 26049409
HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.
Okada Y, Yamazaki K, Umeno J, Takahashi A, Kumasaka N, Ashikawa K, Aoi T, Takazoe M, Matsui T, Hirano A, Matsumoto T, Kamatani N, Nakamura Y, Yamamoto K, Kubo M. Okada Y, et al. Among authors: hirano a. Gastroenterology. 2011 Sep;141(3):864-871.e1-5. doi: 10.1053/j.gastro.2011.05.048. Epub 2011 Jul 19. Gastroenterology. 2011. PMID: 21699788
A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
Yamazaki K, Umeno J, Takahashi A, Hirano A, Johnson TA, Kumasaka N, Morizono T, Hosono N, Kawaguchi T, Takazoe M, Yamada T, Suzuki Y, Tanaka H, Motoya S, Hosokawa M, Arimura Y, Shinomura Y, Matsui T, Matsumoto T, Iida M, Tsunoda T, Nakamura Y, Kamatani N, Kubo M. Yamazaki K, et al. Among authors: hirano a. Gastroenterology. 2013 Apr;144(4):781-8. doi: 10.1053/j.gastro.2012.12.021. Epub 2012 Dec 22. Gastroenterology. 2013. PMID: 23266558
A Genome-wide Association Study Identifying RAP1A as a Novel Susceptibility Gene for Crohn's Disease in Japanese Individuals.
Kakuta Y, Kawai Y, Naito T, Hirano A, Umeno J, Fuyuno Y, Liu Z, Li D, Nakano T, Izumiyama Y, Ichikawa R, Okamoto D, Nagai H, Matsumoto S, Yamamoto K, Yokoyama N, Chiba H, Shimoyama Y, Onodera M, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Endo K, Negoro K, Yasuda J, Esaki M, Tokunaga K, Nakamura M, Matsumoto T, McGovern DPB, Nagasaki M, Kinouchi Y, Shimosegawa T, Masamune A. Kakuta Y, et al. Among authors: hirano a. J Crohns Colitis. 2019 Apr 26;13(5):648-658. doi: 10.1093/ecco-jcc/jjy197. J Crohns Colitis. 2019. PMID: 30500874 Free PMC article.
The gene-treatment interaction of paraoxonase-1 gene polymorphism and statin therapy on insulin secretion in Japanese patients with type 2 diabetes: Fukuoka diabetes registry.
Sumi A, Nakamura U, Iwase M, Fujii H, Ohkuma T, Ide H, Jodai-Kitamura T, Komorita Y, Yoshinari M, Hirakawa Y, Hirano A, Kubo M, Kitazono T. Sumi A, et al. Among authors: hirano a. BMC Med Genet. 2017 Dec 12;18(1):146. doi: 10.1186/s12881-017-0509-1. BMC Med Genet. 2017. PMID: 29233102 Free PMC article. Clinical Trial.
Genetic Analysis of Ulcerative Colitis in Japanese Individuals Using Population-specific SNP Array.
Okamoto D, Kawai Y, Kakuta Y, Naito T, Torisu T, Hirano A, Umeno J, Fuyuno Y, Li D, Nakano T, Izumiyama Y, Ichikawa R, Hiramoto K, Moroi R, Kuroha M, Kanazawa Y, Shiga H, Tokunaga K, Nakamura M, Esaki M, Matsumoto T, McGovern DPB, Nagasaki M, Kinouchi Y, Masamune A. Okamoto D, et al. Among authors: hirano a. Inflamm Bowel Dis. 2020 Jul 17;26(8):1177-1187. doi: 10.1093/ibd/izaa033. Inflamm Bowel Dis. 2020. PMID: 32072174
An Integrated Genomic and Transcriptomic Analysis Reveals Candidates of Susceptibility Genes for Crohn's Disease in Japanese Populations.
Kakuta Y, Ichikawa R, Fuyuno Y, Hirano A, Umeno J, Torisu T, Watanabe K, Asakura A, Nakano T, Izumiyama Y, Okamoto D, Naito T, Moroi R, Kuroha M, Kanazawa Y, Kimura T, Shiga H, Naito T, Esaki M, Kawai Y, Tokunaga K, Nakamura M, Matsumoto T, Nagasaki M, Kinouchi Y, Unno M, Masamune A. Kakuta Y, et al. Among authors: hirano a. Sci Rep. 2020 Jun 24;10(1):10236. doi: 10.1038/s41598-020-66951-5. Sci Rep. 2020. PMID: 32581322 Free PMC article.
1,301 results