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SUMO1 Affects Synaptic Function, Spine Density and Memory.
Matsuzaki S, Lee L, Knock E, Srikumar T, Sakurai M, Hazrati LN, Katayama T, Staniszewski A, Raught B, Arancio O, Fraser PE. Matsuzaki S, et al. Among authors: fraser pe. Sci Rep. 2015 May 29;5:10730. doi: 10.1038/srep10730. Sci Rep. 2015. PMID: 26022678 Free PMC article.
Both the sequence and length of the C terminus of PEN-2 are critical for intermolecular interactions and function of presenilin complexes.
Hasegawa H, Sanjo N, Chen F, Gu YJ, Shier C, Petit A, Kawarai T, Katayama T, Schmidt SD, Mathews PM, Schmitt-Ulms G, Fraser PE, St George-Hyslop P. Hasegawa H, et al. Among authors: fraser pe. J Biol Chem. 2004 Nov 5;279(45):46455-63. doi: 10.1074/jbc.M406289200. Epub 2004 Aug 17. J Biol Chem. 2004. PMID: 15322109 Free article.
SUMO and Alzheimer's disease.
Lee L, Sakurai M, Matsuzaki S, Arancio O, Fraser P. Lee L, et al. Neuromolecular Med. 2013 Dec;15(4):720-36. doi: 10.1007/s12017-013-8257-7. Epub 2013 Aug 25. Neuromolecular Med. 2013. PMID: 23979993 Free PMC article. Review.
Jump from pre-mutation to pathologic expansion in C9orf72.
Xi Z, van Blitterswijk M, Zhang M, McGoldrick P, McLean JR, Yunusova Y, Knock E, Moreno D, Sato C, McKeever PM, Schneider R, Keith J, Petrescu N, Fraser P, Tartaglia MC, Baker MC, Graff-Radford NR, Boylan KB, Dickson DW, Mackenzie IR, Rademakers R, Robertson J, Zinman L, Rogaeva E. Xi Z, et al. Am J Hum Genet. 2015 Jun 4;96(6):962-70. doi: 10.1016/j.ajhg.2015.04.016. Epub 2015 May 21. Am J Hum Genet. 2015. PMID: 26004200 Free PMC article.
Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory.
Fá M, Puzzo D, Piacentini R, Staniszewski A, Zhang H, Baltrons MA, Li Puma DD, Chatterjee I, Li J, Saeed F, Berman HL, Ripoli C, Gulisano W, Gonzalez J, Tian H, Costa JA, Lopez P, Davidowitz E, Yu WH, Haroutunian V, Brown LM, Palmeri A, Sigurdsson EM, Duff KE, Teich AF, Honig LS, Sierks M, Moe JG, D'Adamio L, Grassi C, Kanaan NM, Fraser PE, Arancio O. Fá M, et al. Among authors: fraser pe. Sci Rep. 2016 Jan 20;6:19393. doi: 10.1038/srep19393. Sci Rep. 2016. PMID: 26786552 Free PMC article.
251 results