Hakkarainen J - Search Results

1

Hydroxysteroid (17β)-dehydrogenase 1-deficient female mice present with normal puberty onset but are severely subfertile due to a defect in luteinization and progesterone production.

Hakkarainen J, Jokela H, Pakarinen P, Heikelä H, Kätkänaho L, Vandenput L, Ohlsson C, Zhang FP, Poutanen M. Hakkarainen J, et al. FASEB J. 2015 Sep;29(9):3806-16. doi: 10.1096/fj.14-269035. Epub 2015 May 27. FASEB J. 2015. PMID: 26018678

2

The lack of HSD17B3 in male mice results in disturbed Leydig cell maturation and endocrine imbalance akin to humans with HSD17B3 deficiency.

Sipilä P, Junnila A, Hakkarainen J, Huhtaniemi R, Mairinoja L, Zhang FP, Strauss L, Ohlsson C, Kotaja N, Huhtaniemi I, Poutanen M. Sipilä P, et al. Among authors: hakkarainen j. FASEB J. 2020 May;34(5):6111-6128. doi: 10.1096/fj.201902384R. Epub 2020 Mar 19. FASEB J. 2020. PMID: 32190925

3

Hydroxysteroid (17β) dehydrogenase 1 expressed by Sertoli cells contributes to steroid synthesis and is required for male fertility.

Hakkarainen J, Zhang FP, Jokela H, Mayerhofer A, Behr R, Cisneros-Montalvo S, Nurmio M, Toppari J, Ohlsson C, Kotaja N, Sipilä P, Poutanen M. Hakkarainen J, et al. FASEB J. 2018 Jun;32(6):3229-3241. doi: 10.1096/fj.201700921R. Epub 2018 Jan 24. FASEB J. 2018. PMID: 29401623

These results revealed a novel role for HSD17B1 in the control of spermatogenesis and male fertility, and that Sertoli cells significantly contribute to steroid synthesis in the testis.-Hakkarainen, J., Zhang, F.-P., Jokela, H., Mayerhofer, A., Behr, R., Cisneros-Mo …

These results revealed a novel role for HSD17B1 in the control of spermatogenesis and male fertility, and that Sertoli cells significantly c …

4

Deleting the mouse Hsd17b1 gene results in a hypomorphic Naglu allele and a phenotype mimicking a lysosomal storage disease.

Jokela H, Hakkarainen J, Kätkänaho L, Pakarinen P, Ruohonen ST, Tena-Sempere M, Zhang FP, Poutanen M. Jokela H, et al. Among authors: hakkarainen j. Sci Rep. 2017 Nov 27;7(1):16406. doi: 10.1038/s41598-017-16618-5. Sci Rep. 2017. PMID: 29180785 Free PMC article.

5

HSD17B1 expression induces inflammation-aided rupture of mammary gland myoepithelium.

Järvensivu P, Heinosalo T, Hakkarainen J, Kronqvist P, Saarinen N, Poutanen M. Järvensivu P, et al. Among authors: hakkarainen j. Endocr Relat Cancer. 2018 Apr;25(4):393-406. doi: 10.1530/ERC-17-0476. Epub 2018 Jan 25. Endocr Relat Cancer. 2018. PMID: 29371331 Free article.

6

HSD17B1 Compensates for HSD17B3 Deficiency in Fetal Mouse Testis but Not in Adults.

Junnila A, Zhang FP, Martínez Nieto G, Hakkarainen J, Mäkelä JA, Ohlsson C, Sipilä P, Poutanen M. Junnila A, et al. Among authors: hakkarainen j. Endocrinology. 2024 Apr 29;165(6):bqae056. doi: 10.1210/endocr/bqae056. Endocrinology. 2024. PMID: 38785348

7

Satellites capture socioeconomic disruptions during the 2022 full-scale war in Ukraine.

Ialongo I, Bun R, Hakkarainen J, Virta H, Oda T. Ialongo I, et al. Among authors: hakkarainen j. Sci Rep. 2023 Sep 22;13(1):14954. doi: 10.1038/s41598-023-42118-w. Sci Rep. 2023. PMID: 37737292 Free PMC article.

8

Detection of Anthropogenic CO₂ Emission Signatures with TanSat CO₂ and with Copernicus Sentinel-5 Precursor (S5P) NO₂ Measurements: First Results.

Yang D, Hakkarainen J, Liu Y, Ialongo I, Cai Z, Tamminen J. Yang D, et al. Among authors: hakkarainen j. Adv Atmos Sci. 2023;40(1):1-5. doi: 10.1007/s00376-022-2237-5. Epub 2022 Oct 25. Adv Atmos Sci. 2023. PMID: 36312903 Free PMC article.

9

Setting the record straight-Correcting uterine cancer incidence and mortality in the Nordic countries by reallocation of unspecified cases.

Partanen VM, Heinävaara S, Anttila A, Hakkarainen J, Lönnberg S. Partanen VM, et al. Among authors: hakkarainen j. Acta Obstet Gynecol Scand. 2022 Mar;101(3):323-333. doi: 10.1111/aogs.14314. Epub 2022 Jan 18. Acta Obstet Gynecol Scand. 2022. PMID: 35040121 Free PMC article.

10

Poly(lactic-co-glycolic acid) Nanoparticles Encapsulating the Prenylated Flavonoid, Xanthohumol, Protect Corneal Epithelial Cells from Dry Eye Disease-Associated Oxidative Stress.

Ghosh AK, Thapa R, Hariani HN, Volyanyuk M, Ogle SD, Orloff KA, Ankireddy S, Lai K, Žiniauskaitė A, Stubbs EB Jr, Kalesnykas G, Hakkarainen JJ, Langert KA, Kaja S. Ghosh AK, et al. Among authors: hakkarainen jj. Pharmaceutics. 2021 Aug 30;13(9):1362. doi: 10.3390/pharmaceutics13091362. Pharmaceutics. 2021. PMID: 34575438 Free PMC article.

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