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Stress-free automatic sleep deprivation using air puffs.
Gross BA, Vanderheyden WM, Urpa LM, Davis DE, Fitzpatrick CJ, Prabhu K, Poe GR. Gross BA, et al. Among authors: urpa lm. J Neurosci Methods. 2015 Aug 15;251:83-91. doi: 10.1016/j.jneumeth.2015.05.010. Epub 2015 May 23. J Neurosci Methods. 2015. PMID: 26014662 Free PMC article.
The bradykinin system in stress and anxiety in humans and mice.
Rouhiainen A, Kulesskaya N, Mennesson M, Misiewicz Z, Sipilä T, Sokolowska E, Trontti K, Urpa L, McEntegart W, Saarnio S, Hyytiä P, Hovatta I. Rouhiainen A, et al. Sci Rep. 2019 Dec 19;9(1):19437. doi: 10.1038/s41598-019-55947-5. Sci Rep. 2019. PMID: 31857655 Free PMC article.
A novel variant in SMG9 causes intellectual disability, confirming a role for nonsense-mediated decay components in neurocognitive development.
Rahikkala E, Urpa L, Ghimire B, Topa H, Kurki MI, Koskela M, Airavaara M, Hämäläinen E, Pylkäs K, Körkkö J, Savolainen H, Suoranta A, Bertoli-Avella A, Rolfs A, Mattila P, Daly M, Palotie A, Pietiläinen O, Moilanen J, Kuismin O. Rahikkala E, et al. Eur J Hum Genet. 2022 May;30(5):619-627. doi: 10.1038/s41431-022-01046-5. Epub 2022 Jan 28. Eur J Hum Genet. 2022. PMID: 35087184 Free PMC article.
Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants.
Saarentaus EC, Havulinna AS, Mars N, Ahola-Olli A, Kiiskinen TTJ, Partanen J, Ruotsalainen S, Kurki M, Urpa LM, Chen L, Perola M, Salomaa V, Veijola J, Männikkö M, Hall IM, Pietiläinen O, Kaprio J, Ripatti S, Daly M, Palotie A. Saarentaus EC, et al. Among authors: urpa lm. Mol Psychiatry. 2021 Sep;26(9):4884-4895. doi: 10.1038/s41380-021-01026-z. Epub 2021 Feb 1. Mol Psychiatry. 2021. PMID: 33526825 Free PMC article.
Functional Characterization of Six SLCO1B1 (OATP1B1) Variants Observed in Finnish Individuals with a Psychotic Disorder.
Häkkinen K, Kiander W, Kidron H, Lähteenvuo M, Urpa L, Lintunen J, Vellonen KS, Auriola S, Holm M, Lahdensuo K, Kampman O, Isometsä E, Kieseppä T, Lönnqvist J, Suvisaari J, Hietala J, Tiihonen J, Palotie A, Ahola-Olli AV, Niemi M. Häkkinen K, et al. Mol Pharm. 2023 Mar 6;20(3):1500-1508. doi: 10.1021/acs.molpharmaceut.2c00715. Epub 2023 Feb 13. Mol Pharm. 2023. PMID: 36779498 Free PMC article.