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ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis.
Dey S, Sayers CM, Verginadis II, Lehman SL, Cheng Y, Cerniglia GJ, Tuttle SW, Feldman MD, Zhang PJ, Fuchs SY, Diehl JA, Koumenis C. Dey S, et al. Among authors: verginadis ii. J Clin Invest. 2015 Jul 1;125(7):2592-608. doi: 10.1172/JCI78031. Epub 2015 May 26. J Clin Invest. 2015. PMID: 26011642 Free PMC article.
ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.
Tameire F, Verginadis II, Leli NM, Polte C, Conn CS, Ojha R, Salas Salinas C, Chinga F, Monroy AM, Fu W, Wang P, Kossenkov A, Ye J, Amaravadi RK, Ignatova Z, Fuchs SY, Diehl JA, Ruggero D, Koumenis C. Tameire F, et al. Among authors: verginadis ii. Nat Cell Biol. 2019 Jul;21(7):889-899. doi: 10.1038/s41556-019-0347-9. Epub 2019 Jul 1. Nat Cell Biol. 2019. PMID: 31263264 Free PMC article.
Author Correction: ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.
Tameire F, Verginadis II, Leli NM, Polte C, Conn CS, Ojha R, Salinas CS, Chinga F, Monroy AM, Fu W, Wang P, Kossenkov A, Ye J, Amaravadi RK, Ignatova Z, Fuchs SY, Diehl JA, Ruggero D, Koumenis C. Tameire F, et al. Among authors: verginadis ii. Nat Cell Biol. 2019 Aug;21(8):1052. doi: 10.1038/s41556-019-0370-x. Nat Cell Biol. 2019. PMID: 31316187
Regulation of intercellular biomolecule transfer-driven tumor angiogenesis and responses to anticancer therapies.
Lu Z, Ortiz A, Verginadis II, Peck AR, Zahedi F, Cho C, Yu P, DeRita RM, Zhang H, Kubanoff R, Sun Y, Yaspan AT, Krespan E, Beiting DP, Radaelli E, Ryeom SW, Diehl JA, Rui H, Koumenis C, Fuchs SY. Lu Z, et al. Among authors: verginadis ii. J Clin Invest. 2021 May 17;131(10):e144225. doi: 10.1172/JCI144225. J Clin Invest. 2021. PMID: 33998600 Free PMC article.
A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression.
Verginadis II, Avgousti H, Monslow J, Skoufos G, Chinga F, Kim K, Leli NM, Karagounis IV, Bell BI, Velalopoulou A, Salinas CS, Wu VS, Li Y, Ye J, Scott DA, Osterman AL, Sengupta A, Weljie A, Huang M, Zhang D, Fan Y, Radaelli E, Tobias JW, Rambow F, Karras P, Marine JC, Xu X, Hatzigeorgiou AG, Ryeom S, Diehl JA, Fuchs SY, Puré E, Koumenis C. Verginadis II, et al. Nat Cell Biol. 2022 Jun;24(6):940-953. doi: 10.1038/s41556-022-00918-8. Epub 2022 Jun 2. Nat Cell Biol. 2022. PMID: 35654839 Free PMC article.
Induction of the activating transcription factor-4 in the intratumoral CD8+ T cells sustains their viability and anti-tumor activities.
Lu Z, Bae EA, Verginadis II, Zhang H, Cho C, McBrearty N, George SS, Diehl JA, Koumenis C, Bradley LM, Fuchs SY. Lu Z, et al. Among authors: verginadis ii. Cancer Immunol Immunother. 2023 Apr;72(4):815-826. doi: 10.1007/s00262-022-03286-2. Epub 2022 Sep 5. Cancer Immunol Immunother. 2023. PMID: 36063172 Free PMC article.
49 results