Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

168 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA, Patel V, Clish CB, Sullivan WJ Jr, Zhou H, Bopp SE, Schimmel P, Lindquist S, Clardy J, Mota MM, Keller TL, Whitman M, Wiest O, Wirth DF, Mazitschek R. Herman JD, et al. Among authors: mota mm. Sci Transl Med. 2015 May 20;7(288):288ra77. doi: 10.1126/scitranslmed.aaa3575. Sci Transl Med. 2015. PMID: 25995223 Free PMC article.
The next opportunity in anti-malaria drug discovery: the liver stage.
Derbyshire ER, Mota MM, Clardy J. Derbyshire ER, et al. Among authors: mota mm. PLoS Pathog. 2011 Sep;7(9):e1002178. doi: 10.1371/journal.ppat.1002178. Epub 2011 Sep 22. PLoS Pathog. 2011. PMID: 21966266 Free PMC article. No abstract available.
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
Derbyshire ER, Prudêncio M, Mota MM, Clardy J. Derbyshire ER, et al. Among authors: mota mm. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8511-6. doi: 10.1073/pnas.1118370109. Epub 2012 May 14. Proc Natl Acad Sci U S A. 2012. PMID: 22586124 Free PMC article.
Quinolin-4(1H)-imines are potent antiplasmodial drugs targeting the liver stage of malaria.
Rodrigues T, da Cruz FP, Lafuente-Monasterio MJ, Gonçalves D, Ressurreição AS, Sitoe AR, Bronze MR, Gut J, Schneider G, Mota MM, Rosenthal PJ, Prudêncio M, Gamo FJ, Lopes F, Moreira R. Rodrigues T, et al. Among authors: mota mm. J Med Chem. 2013 Jun 13;56(11):4811-5. doi: 10.1021/jm400246e. Epub 2013 May 23. J Med Chem. 2013. PMID: 23701465
Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins.
Hanson KK, Ressurreição AS, Buchholz K, Prudêncio M, Herman-Ornelas JD, Rebelo M, Beatty WL, Wirth DF, Hänscheid T, Moreira R, Marti M, Mota MM. Hanson KK, et al. Among authors: mota mm. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):E2838-47. doi: 10.1073/pnas.1306097110. Epub 2013 Jul 8. Proc Natl Acad Sci U S A. 2013. PMID: 23836641 Free PMC article.
Structural optimization of quinolon-4(1H)-imines as dual-stage antimalarials: toward increased potency and metabolic stability.
Ressurreição AS, Gonçalves D, Sitoe AR, Albuquerque IS, Gut J, Góis A, Gonçalves LM, Bronze MR, Hanscheid T, Biagini GA, Rosenthal PJ, Prudêncio M, O'Neill P, Mota MM, Lopes F, Moreira R. Ressurreição AS, et al. Among authors: mota mm. J Med Chem. 2013 Oct 10;56(19):7679-90. doi: 10.1021/jm4011466. Epub 2013 Sep 30. J Med Chem. 2013. PMID: 24020770
168 results