Thathiah A - Search Results

1

Regulation of neuronal communication by G protein-coupled receptors.

Huang Y, Thathiah A. Huang Y, et al. Among authors: thathiah a. FEBS Lett. 2015 Jun 22;589(14):1607-19. doi: 10.1016/j.febslet.2015.05.007. Epub 2015 May 14. FEBS Lett. 2015. PMID: 25980603 Free article. Review.

2

The role of GPCRs in neurodegenerative diseases: avenues for therapeutic intervention.

Huang Y, Todd N, Thathiah A. Huang Y, et al. Among authors: thathiah a. Curr Opin Pharmacol. 2017 Feb;32:96-110. doi: 10.1016/j.coph.2017.02.001. Epub 2017 Mar 10. Curr Opin Pharmacol. 2017. PMID: 28288370 Review.

3

β-arrestin 2 regulates Aβ generation and γ-secretase activity in Alzheimer's disease.

Thathiah A, Horré K, Snellinx A, Vandewyer E, Huang Y, Ciesielska M, De Kloe G, Munck S, De Strooper B. Thathiah A, et al. Nat Med. 2013 Jan;19(1):43-9. doi: 10.1038/nm.3023. Epub 2012 Dec 2. Nat Med. 2013. PMID: 23202293 Free article.

4

Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models.

Huang Y, Skwarek-Maruszewska A, Horré K, Vandewyer E, Wolfs L, Snellinx A, Saito T, Radaelli E, Corthout N, Colombelli J, Lo AC, Van Aerschot L, Callaerts-Vegh Z, Trabzuni D, Bossers K, Verhaagen J, Ryten M, Munck S, D'Hooge R, Swaab DF, Hardy J, Saido TC, De Strooper B, Thathiah A. Huang Y, et al. Among authors: thathiah a. Sci Transl Med. 2015 Oct 14;7(309):309ra164. doi: 10.1126/scitranslmed.aab3492. Sci Transl Med. 2015. PMID: 26468326

5

GPCR kinases generate an APH1A phosphorylation barcode to regulate amyloid-β generation.

Todd NK, Huang Y, Lee JY, Doruker P, Krieger JM, Salisbury R, MacDonald M, Bahar I, Thathiah A. Todd NK, et al. Among authors: thathiah a. Cell Rep. 2022 Jul 19;40(3):111110. doi: 10.1016/j.celrep.2022.111110. Cell Rep. 2022. PMID: 35858570 Free PMC article.

6

G protein-biased GPR3 signaling ameliorates amyloid pathology in a preclinical Alzheimer's disease mouse model.

Huang Y, Rafael Guimarães T, Todd N, Ferguson C, Weiss KM, Stauffer FR, McDermott B, Hurtle BT, Saito T, Saido TC, MacDonald ML, Homanics GE, Thathiah A. Huang Y, et al. Among authors: thathiah a. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2204828119. doi: 10.1073/pnas.2204828119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161942 Free PMC article.

7

The role of G protein-coupled receptors in the pathology of Alzheimer's disease.

Thathiah A, De Strooper B. Thathiah A, et al. Nat Rev Neurosci. 2011 Feb;12(2):73-87. doi: 10.1038/nrn2977. Nat Rev Neurosci. 2011. PMID: 21248787 Review.

8

G protein-coupled receptors, cholinergic dysfunction, and Abeta toxicity in Alzheimer's disease.

Thathiah A, De Strooper B. Thathiah A, et al. Sci Signal. 2009 Oct 20;2(93):re8. doi: 10.1126/scisignal.293re8. Sci Signal. 2009. PMID: 19843960 Review.

9

The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons.

Thathiah A, Spittaels K, Hoffmann M, Staes M, Cohen A, Horré K, Vanbrabant M, Coun F, Baekelandt V, Delacourte A, Fischer DF, Pollet D, De Strooper B, Merchiers P. Thathiah A, et al. Science. 2009 Feb 13;323(5916):946-51. doi: 10.1126/science.1160649. Science. 2009. PMID: 19213921

10

Regulation of amyloid precursor protein processing by serotonin signaling.

Pimenova AA, Thathiah A, De Strooper B, Tesseur I. Pimenova AA, et al. Among authors: thathiah a. PLoS One. 2014 Jan 21;9(1):e87014. doi: 10.1371/journal.pone.0087014. eCollection 2014. PLoS One. 2014. PMID: 24466315 Free PMC article.

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