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Neuropeptide FF receptors as novel targets for limbic seizure attenuation.
Portelli J, Meurs A, Bihel F, Hammoud H, Schmitt M, De Kock J, Utard V, Humbert JP, Bertin I, Buffel I, Coppens J, Tourwe D, Maes V, De Prins A, Vanhaecke T, Massie A, Balasubramaniam A, Boon P, Bourguignon JJ, Simonin F, Smolders I. Portelli J, et al. Among authors: simonin f. Neuropharmacology. 2015 Aug;95:415-23. doi: 10.1016/j.neuropharm.2015.04.030. Epub 2015 May 9. Neuropharmacology. 2015. PMID: 25963417
RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia.
Simonin F, Schmitt M, Laulin JP, Laboureyras E, Jhamandas JH, MacTavish D, Matifas A, Mollereau C, Laurent P, Parmentier M, Kieffer BL, Bourguignon JJ, Simonnet G. Simonin F, et al. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):466-71. doi: 10.1073/pnas.0502090103. Epub 2006 Jan 3. Proc Natl Acad Sci U S A. 2006. PMID: 16407169 Free PMC article.
Development of sub-nanomolar dipeptidic ligands of neuropeptide FF receptors.
Gealageas R, Schneider S, Humbert JP, Bertin I, Schmitt M, Laboureyras E, Dugave C, Mollereau C, Simonnet G, Bourguignon JJ, Simonin F, Bihel F. Gealageas R, et al. Among authors: simonin f. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7471-4. doi: 10.1016/j.bmcl.2012.10.049. Epub 2012 Oct 17. Bioorg Med Chem Lett. 2012. PMID: 23131340
Endogenous mammalian RF-amide peptides, including PrRP, kisspeptin and 26RFa, modulate nociception and morphine analgesia via NPFF receptors.
Elhabazi K, Humbert JP, Bertin I, Schmitt M, Bihel F, Bourguignon JJ, Bucher B, Becker JA, Sorg T, Meziane H, Petit-Demoulière B, Ilien B, Simonin F. Elhabazi K, et al. Among authors: simonin f. Neuropharmacology. 2013 Dec;75:164-71. doi: 10.1016/j.neuropharm.2013.07.012. Epub 2013 Aug 2. Neuropharmacology. 2013. PMID: 23911743
72 results