Issinger OG - Search Results

1

A Note of Caution on the Role of Halogen Bonds for Protein Kinase/Inhibitor Recognition Suggested by High- And Low-Salt CK2α Complex Structures.

Guerra B, Bischoff N, Bdzhola VG, Yarmoluk SM, Issinger OG, Golub AG, Niefind K. Guerra B, et al. Among authors: issinger og. ACS Chem Biol. 2015 Jul 17;10(7):1654-60. doi: 10.1021/acschembio.5b00235. Epub 2015 May 15. ACS Chem Biol. 2015. PMID: 25961323

2

Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate.

Yde CW, Ermakova I, Issinger OG, Niefind K. Yde CW, et al. Among authors: issinger og. J Mol Biol. 2005 Mar 25;347(2):399-414. doi: 10.1016/j.jmb.2005.01.003. Epub 2005 Jan 18. J Mol Biol. 2005. PMID: 15740749

3

Protein kinase CK2 in human diseases.

Guerra B, Issinger OG. Guerra B, et al. Among authors: issinger og. Curr Med Chem. 2008;15(19):1870-86. doi: 10.2174/092986708785132933. Curr Med Chem. 2008. PMID: 18691045 Review.

4

First inactive conformation of CK2 alpha, the catalytic subunit of protein kinase CK2.

Raaf J, Issinger OG, Niefind K. Raaf J, et al. Among authors: issinger og. J Mol Biol. 2009 Mar 13;386(5):1212-21. doi: 10.1016/j.jmb.2009.01.033. Epub 2009 Jan 24. J Mol Biol. 2009. PMID: 19361447

5

Conformational plasticity of the catalytic subunit of protein kinase CK2 and its consequences for regulation and drug design.

Niefind K, Issinger OG. Niefind K, et al. Among authors: issinger og. Biochim Biophys Acta. 2010 Mar;1804(3):484-92. doi: 10.1016/j.bbapap.2009.09.022. Epub 2009 Sep 28. Biochim Biophys Acta. 2010. PMID: 19796713 Review.

6

Structural basis of the constitutive activity of protein kinase CK2.

Olsen BB, Guerra B, Niefind K, Issinger OG. Olsen BB, et al. Among authors: issinger og. Methods Enzymol. 2010;484:515-29. doi: 10.1016/B978-0-12-381298-8.00025-3. Methods Enzymol. 2010. PMID: 21036248

7

Low-density crystal packing of human protein kinase CK2 catalytic subunit in complex with resorufin or other ligands: a tool to study the unique hinge-region plasticity of the enzyme without packing bias.

Klopffleisch K, Issinger OG, Niefind K. Klopffleisch K, et al. Among authors: issinger og. Acta Crystallogr D Biol Crystallogr. 2012 Aug;68(Pt 8):883-92. doi: 10.1107/S0907444912016587. Epub 2012 Jul 7. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22868753 Free article.

8

First structure of protein kinase CK2 catalytic subunit with an effective CK2β-competitive ligand.

Raaf J, Guerra B, Neundorf I, Bopp B, Issinger OG, Jose J, Pietsch M, Niefind K. Raaf J, et al. Among authors: issinger og. ACS Chem Biol. 2013 May 17;8(5):901-7. doi: 10.1021/cb3007133. Epub 2013 Mar 18. ACS Chem Biol. 2013. PMID: 23474121

9

The protein kinase CK2(Andante) holoenzyme structure supports proposed models of autoregulation and trans-autophosphorylation.

Schnitzler A, Olsen BB, Issinger OG, Niefind K. Schnitzler A, et al. Among authors: issinger og. J Mol Biol. 2014 May 1;426(9):1871-82. doi: 10.1016/j.jmb.2014.02.018. Epub 2014 Mar 1. J Mol Biol. 2014. PMID: 24594356

10

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.

Ermakova I, Boldyreff B, Issinger OG, Niefind K. Ermakova I, et al. Among authors: issinger og. J Mol Biol. 2003 Jul 25;330(5):925-34. doi: 10.1016/s0022-2836(03)00638-7. J Mol Biol. 2003. PMID: 12860116

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