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4,065 results

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Page 1
Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.
Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M. Grasso CS, et al. Among authors: mao h. Nat Med. 2015 Jun;21(6):555-9. doi: 10.1038/nm.3855. Epub 2015 May 4. Nat Med. 2015. PMID: 25939062 Free PMC article.
Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.
Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M. Grasso CS, et al. Among authors: mao h. Nat Med. 2015 Jul;21(7):827. doi: 10.1038/nm0715-827a. Nat Med. 2015. PMID: 26151328 No abstract available.
A patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children.
Liu Z, Zhao X, Wang Y, Mao H, Huang Y, Kogiso M, Qi L, Baxter PA, Man TK, Adesina A, Su JM, Picard D, Ching Ho K, Huang A, Perlaky L, Lau CC, Chintagumpala M, Li XN. Liu Z, et al. Among authors: mao h. Neuro Oncol. 2014 Jun;16(6):787-99. doi: 10.1093/neuonc/not244. Epub 2014 Jan 26. Neuro Oncol. 2014. PMID: 24470556 Free PMC article.
Preservation of KIT genotype in a novel pair of patient-derived orthotopic xenograft mouse models of metastatic pediatric CNS germinoma.
Lindsay H, Huang Y, Du Y, Braun FK, Teo WY, Kogiso M, Qi L, Zhang H, Zhao S, Mao H, Lin F, Baxter P, Su JM, Terashima K, Perlaky L, Chintagumpala M, Adesina A, Lau CC, Williams Parsons D, Li XN. Lindsay H, et al. Among authors: mao h. J Neurooncol. 2016 May;128(1):47-56. doi: 10.1007/s11060-016-2098-9. Epub 2016 Mar 8. J Neurooncol. 2016. PMID: 26956263 Free PMC article.
Silencing BMI1 eliminates tumor formation of pediatric glioma CD133+ cells not by affecting known targets but by down-regulating a novel set of core genes.
Baxter PA, Lin Q, Mao H, Kogiso M, Zhao X, Liu Z, Huang Y, Voicu H, Gurusiddappa S, Su JM, Adesina AM, Perlaky L, Dauser RC, Leung HC, Muraszko KM, Heth JA, Fan X, Lau CC, Man TK, Chintagumpala M, Li XN. Baxter PA, et al. Among authors: mao h. Acta Neuropathol Commun. 2014 Dec 20;2:160. doi: 10.1186/s40478-014-0160-4. Acta Neuropathol Commun. 2014. PMID: 25526772 Free PMC article.
Intravenous injection of oncolytic picornavirus SVV-001 prolongs animal survival in a panel of primary tumor-based orthotopic xenograft mouse models of pediatric glioma.
Liu Z, Zhao X, Mao H, Baxter PA, Huang Y, Yu L, Wadhwa L, Su JM, Adesina A, Perlaky L, Hurwitz M, Idamakanti N, Police SR, Hallenbeck PL, Hurwitz RL, Lau CC, Chintagumpala M, Blaney SM, Li XN. Liu Z, et al. Among authors: mao h. Neuro Oncol. 2013 Sep;15(9):1173-85. doi: 10.1093/neuonc/not065. Epub 2013 May 7. Neuro Oncol. 2013. PMID: 23658322 Free PMC article.
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes.
Yeo MJ, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N. Yeo MJ, et al. Among authors: mao h. bioRxiv [Preprint]. 2024 May 14:2024.05.14.593897. doi: 10.1101/2024.05.14.593897. bioRxiv. 2024. PMID: 38798619 Free PMC article. Preprint.
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes.
Xie X, Zhang O, Yeo MJR, Lee C, Harry SA, Paul L, Li Y, Payne NC, Nam E, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB. Xie X, et al. Among authors: mao h. bioRxiv [Preprint]. 2024 May 14:2024.05.14.593970. doi: 10.1101/2024.05.14.593970. bioRxiv. 2024. PMID: 38798357 Free PMC article. Preprint.
4,065 results