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Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.
Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M. Grasso CS, et al. Among authors: le dret l. Nat Med. 2015 Jun;21(6):555-9. doi: 10.1038/nm.3855. Epub 2015 May 4. Nat Med. 2015. PMID: 25939062 Free PMC article.
Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma.
Truffaux N, Philippe C, Paulsson J, Andreiuolo F, Guerrini-Rousseau L, Cornilleau G, Le Dret L, Richon C, Lacroix L, Puget S, Geoerger B, Vassal G, Östman A, Grill J. Truffaux N, et al. Among authors: le dret l. Neuro Oncol. 2015 Jul;17(7):953-64. doi: 10.1093/neuonc/nou330. Epub 2014 Dec 21. Neuro Oncol. 2015. PMID: 25534822 Free PMC article.
Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.
Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M. Grasso CS, et al. Among authors: le dret l. Nat Med. 2015 Jul;21(7):827. doi: 10.1038/nm0715-827a. Nat Med. 2015. PMID: 26151328 No abstract available.
Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes.
Castel D, Philippe C, Calmon R, Le Dret L, Truffaux N, Boddaert N, Pagès M, Taylor KR, Saulnier P, Lacroix L, Mackay A, Jones C, Sainte-Rose C, Blauwblomme T, Andreiuolo F, Puget S, Grill J, Varlet P, Debily MA. Castel D, et al. Among authors: le dret l. Acta Neuropathol. 2015 Dec;130(6):815-27. doi: 10.1007/s00401-015-1478-0. Epub 2015 Sep 23. Acta Neuropathol. 2015. PMID: 26399631 Free PMC article.
New in vivo avatars of diffuse intrinsic pontine gliomas (DIPG) from stereotactic biopsies performed at diagnosis.
Plessier A, Le Dret L, Varlet P, Beccaria K, Lacombe J, Mériaux S, Geffroy F, Fiette L, Flamant P, Chrétien F, Blauwblomme T, Puget S, Grill J, Debily MA, Castel D. Plessier A, et al. Among authors: le dret l. Oncotarget. 2017 Feb 2;8(32):52543-52559. doi: 10.18632/oncotarget.15002. eCollection 2017 Aug 8. Oncotarget. 2017. PMID: 28881750 Free PMC article.
VRK3 depletion induces cell cycle arrest and metabolic reprogramming of pontine diffuse midline glioma - H3K27 altered cells.
Menez V, Kergrohen T, Shasha T, Silva-Evangelista C, Le Dret L, Auffret L, Subecz C, Lancien M, Ajlil Y, Vilchis IS, Beccaria K, Blauwblomme T, Oberlin E, Grill J, Castel D, Debily MA. Menez V, et al. Among authors: le dret l. Front Oncol. 2023 Oct 10;13:1229312. doi: 10.3389/fonc.2023.1229312. eCollection 2023. Front Oncol. 2023. PMID: 37886173 Free PMC article.
13 results