Pepers BA - Search Results

1

Making (anti-) sense out of huntingtin levels in Huntington disease.

Evers MM, Schut MH, Pepers BA, Atalar M, van Belzen MJ, Faull RL, Roos RA, van Roon-Mom WM. Evers MM, et al. Among authors: pepers ba. Mol Neurodegener. 2015 Apr 28;10:21. doi: 10.1186/s13024-015-0018-7. Mol Neurodegener. 2015. PMID: 25928884 Free PMC article.

2

Strong aggregation and increased toxicity of polyleucine over polyglutamine stretches in mammalian cells.

Dorsman JC, Pepers B, Langenberg D, Kerkdijk H, Ijszenga M, den Dunnen JT, Roos RA, van Ommen GJ. Dorsman JC, et al. Hum Mol Genet. 2002 Jun 15;11(13):1487-96. doi: 10.1093/hmg/11.13.1487. Hum Mol Genet. 2002. PMID: 12045202

3

Mutant huntingtin represses CBP, but not p300, by binding and protein degradation.

Cong SY, Pepers BA, Evert BO, Rubinsztein DC, Roos RA, van Ommen GJ, Dorsman JC. Cong SY, et al. Among authors: pepers ba. Mol Cell Neurosci. 2005 Sep;30(1):12-23. doi: 10.1016/j.mcn.2005.05.003. Mol Cell Neurosci. 2005. PMID: 15994095 Corrected and republished.

4

Epitope mapping of monoclonal antibody 4C8 recognizing the protein huntingtin.

Cong SY, Pepers BA, Roos RA, Van Ommen GJ, Dorsman JC. Cong SY, et al. Among authors: pepers ba. Hybridoma (Larchmt). 2005 Oct;24(5):231-5. doi: 10.1089/hyb.2005.24.231. Hybridoma (Larchmt). 2005. PMID: 16225422

5

Small N-terminal mutant huntingtin fragments, but not wild type, are mainly present in monomeric form: Implications for pathogenesis.

Cong SY, Pepers BA, Roos RA, van Ommen GJ, Dorsman JC. Cong SY, et al. Among authors: pepers ba. Exp Neurol. 2006 Jun;199(2):257-64. doi: 10.1016/j.expneurol.2005.11.008. Epub 2005 Dec 27. Exp Neurol. 2006. PMID: 16380118

6

Mutant huntingtin represses CBP, but not p300, by binding and protein degradation.

Cong SY, Pepers BA, Evert BO, Rubinsztein DC, Roos RA, van Ommen GJ, Dorsman JC. Cong SY, et al. Among authors: pepers ba. Mol Cell Neurosci. 2005 Dec;30(4):560-71. Mol Cell Neurosci. 2005. PMID: 16456924

7

Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease.

van Roon-Mom WM, Pepers BA, 't Hoen PA, Verwijmeren CA, den Dunnen JT, Dorsman JC, van Ommen GB. van Roon-Mom WM, et al. Among authors: pepers ba. BMC Mol Biol. 2008 Oct 9;9:84. doi: 10.1186/1471-2199-9-84. BMC Mol Biol. 2008. PMID: 18844975 Free PMC article.

8

Cost-effective HRMA pre-sequence typing of clone libraries; application to phage display selection.

Pepers BA, Schut MH, Vossen RH, van Ommen GJ, den Dunnen JT, van Roon-Mom WM. Pepers BA, et al. BMC Biotechnol. 2009 May 22;9:50. doi: 10.1186/1472-6750-9-50. BMC Biotechnol. 2009. PMID: 19463169 Free PMC article.

9

Targeting several CAG expansion diseases by a single antisense oligonucleotide.

Evers MM, Pepers BA, van Deutekom JC, Mulders SA, den Dunnen JT, Aartsma-Rus A, van Ommen GJ, van Roon-Mom WM. Evers MM, et al. Among authors: pepers ba. PLoS One. 2011;6(9):e24308. doi: 10.1371/journal.pone.0024308. Epub 2011 Sep 1. PLoS One. 2011. PMID: 21909428 Free PMC article.

10

Huntingtin with an expanded polyglutamine repeat affects the Jab1-p27(Kip1) pathway.

Cong SY, Pepers BA, Zhou TT, Kerkdijk H, Roos RA, van Ommen GJ, Dorsman JC. Cong SY, et al. Among authors: pepers ba. Neurobiol Dis. 2012 Jun;46(3):673-81. doi: 10.1016/j.nbd.2012.03.008. Epub 2012 Mar 8. Neurobiol Dis. 2012. PMID: 22426400

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