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Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity.
Carmi Y, Spitzer MH, Linde IL, Burt BM, Prestwood TR, Perlman N, Davidson MG, Kenkel JA, Segal E, Pusapati GV, Bhattacharya N, Engleman EG. Carmi Y, et al. Among authors: spitzer mh. Nature. 2015 May 7;521(7550):99-104. doi: 10.1038/nature14424. Epub 2015 Apr 29. Nature. 2015. PMID: 25924063 Free PMC article.
The transcriptional landscape of αβ T cell differentiation.
Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C; Immunological Genome Consortium; Best AJ, Knell J, Goldrath A, Joic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kim F, Nageswara Rao T, Wagers A, Heng T, Ericson J, Rothamel K, Ortiz-Lopez A, Mathis D, Benoist C, Bezman NA, Sun JC, Min-Oo G, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Monach P, Blair DA, Dustin ML, Shinton SA, Hardy RR, Laidlaw D, Collins J, Gazit R, Rossi DJ, Malhotra N, Sylvia K, Kang J, Kreslavsky T, Fletcher A, Elpek K, Bellemare-Pelletier A, Malhotra D, Turley S. Mingueneau M, et al. Among authors: spitzer mh. Nat Immunol. 2013 Jun;14(6):619-32. doi: 10.1038/ni.2590. Epub 2013 May 5. Nat Immunol. 2013. PMID: 23644507 Free PMC article.
Automated mapping of phenotype space with single-cell data.
Samusik N, Good Z, Spitzer MH, Davis KL, Nolan GP. Samusik N, et al. Among authors: spitzer mh. Nat Methods. 2016 Jun;13(6):493-6. doi: 10.1038/nmeth.3863. Epub 2016 May 16. Nat Methods. 2016. PMID: 27183440 Free PMC article.
Akt and SHP-1 are DC-intrinsic checkpoints for tumor immunity.
Carmi Y, Prestwood TR, Spitzer MH, Linde IL, Chabon J, Reticker-Flynn NE, Bhattacharya N, Zhang H, Zhang X, Basto PA, Burt BM, Alonso MN, Engleman EG. Carmi Y, et al. Among authors: spitzer mh. JCI Insight. 2016 Nov 3;1(18):e89020. doi: 10.1172/jci.insight.89020. JCI Insight. 2016. PMID: 27812544 Free PMC article.
Systemic Immunity Is Required for Effective Cancer Immunotherapy.
Spitzer MH, Carmi Y, Reticker-Flynn NE, Kwek SS, Madhireddy D, Martins MM, Gherardini PF, Prestwood TR, Chabon J, Bendall SC, Fong L, Nolan GP, Engleman EG. Spitzer MH, et al. Cell. 2017 Jan 26;168(3):487-502.e15. doi: 10.1016/j.cell.2016.12.022. Epub 2017 Jan 19. Cell. 2017. PMID: 28111070 Free PMC article.
De novo mutations in mitochondrial DNA of iPSCs produce immunogenic neoepitopes in mice and humans.
Deuse T, Hu X, Agbor-Enoh S, Koch M, Spitzer MH, Gravina A, Alawi M, Marishta A, Peters B, Kosaloglu-Yalcin Z, Yang Y, Rajalingam R, Wang D, Nashan B, Kiefmann R, Reichenspurner H, Valantine H, Weissman IL, Schrepfer S. Deuse T, et al. Among authors: spitzer mh. Nat Biotechnol. 2019 Oct;37(10):1137-1144. doi: 10.1038/s41587-019-0227-7. Epub 2019 Aug 19. Nat Biotechnol. 2019. PMID: 31427818
Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.
Zammit NW, Siggs OM, Gray PE, Horikawa K, Langley DB, Walters SN, Daley SR, Loetsch C, Warren J, Yap JY, Cultrone D, Russell A, Malle EK, Villanueva JE, Cowley MJ, Gayevskiy V, Dinger ME, Brink R, Zahra D, Chaudhri G, Karupiah G, Whittle B, Roots C, Bertram E, Yamada M, Jeelall Y, Enders A, Clifton BE, Mabbitt PD, Jackson CJ, Watson SR, Jenne CN, Lanier LL, Wiltshire T, Spitzer MH, Nolan GP, Schmitz F, Aderem A, Porebski BT, Buckle AM, Abbott DW, Ziegler JB, Craig ME, Benitez-Aguirre P, Teo J, Tangye SG, King C, Wong M, Cox MP, Phung W, Tang J, Sandoval W, Wertz IE, Christ D, Goodnow CC, Grey ST. Zammit NW, et al. Among authors: spitzer mh. Nat Immunol. 2019 Oct;20(10):1299-1310. doi: 10.1038/s41590-019-0492-0. Epub 2019 Sep 18. Nat Immunol. 2019. PMID: 31534238
75 results