Fendrich G - Search Results

1

The Crystal Structure of Cancer Osaka Thyroid Kinase Reveals an Unexpected Kinase Domain Fold.

Gutmann S, Hinniger A, Fendrich G, Drückes P, Antz S, Mattes H, Möbitz H, Ofner S, Schmiedeberg N, Stojanovic A, Rieffel S, Strauss A, Troxler T, Glatthar R, Sparrer H. Gutmann S, et al. Among authors: fendrich g. J Biol Chem. 2015 Jun 12;290(24):15210-8. doi: 10.1074/jbc.M115.648097. Epub 2015 Apr 27. J Biol Chem. 2015. PMID: 25918157 Free PMC article.

2

Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors.

Glatthar R, Stojanovic A, Troxler T, Mattes H, Möbitz H, Beerli R, Blanz J, Gassmann E, Drückes P, Fendrich G, Gutmann S, Martiny-Baron G, Spence F, Hornfeld J, Peel JE, Sparrer H. Glatthar R, et al. Among authors: fendrich g. J Med Chem. 2016 Aug 25;59(16):7544-60. doi: 10.1021/acs.jmedchem.6b00598. Epub 2016 Aug 17. J Med Chem. 2016. PMID: 27502541

3

Solution conformations and dynamics of ABL kinase-inhibitor complexes determined by NMR substantiate the different binding modes of imatinib/nilotinib and dasatinib.

Vajpai N, Strauss A, Fendrich G, Cowan-Jacob SW, Manley PW, Grzesiek S, Jahnke W. Vajpai N, et al. Among authors: fendrich g. J Biol Chem. 2008 Jun 27;283(26):18292-302. doi: 10.1074/jbc.M801337200. Epub 2008 Apr 22. J Biol Chem. 2008. PMID: 18434310 Free article.

4

NMR resonance assignment of selectively labeled proteins by the use of paramagnetic ligands.

Cutting B, Strauss A, Fendrich G, Manley PW, Jahnke W. Cutting B, et al. Among authors: fendrich g. J Biomol NMR. 2004 Oct;30(2):205-10. doi: 10.1023/b:jnmr.0000048947.28598.ea. J Biomol NMR. 2004. PMID: 15702527

5

Improved expression of kinases in Baculovirus-infected insect cells upon addition of specific kinase inhibitors to the culture helpful for structural studies.

Strauss A, Fendrich G, Horisberger MA, Liebetanz J, Meyhack B, Schlaeppi JM, Schmitz R. Strauss A, et al. Among authors: fendrich g. Protein Expr Purif. 2007 Dec;56(2):167-76. doi: 10.1016/j.pep.2007.06.008. Epub 2007 Jul 10. Protein Expr Purif. 2007. PMID: 17720535

6

Efficient uniform isotope labeling of Abl kinase expressed in Baculovirus-infected insect cells.

Strauss A, Bitsch F, Fendrich G, Graff P, Knecht R, Meyhack B, Jahnke W. Strauss A, et al. Among authors: fendrich g. J Biomol NMR. 2005 Apr;31(4):343-9. doi: 10.1007/s10858-005-2451-3. J Biomol NMR. 2005. PMID: 15929001

7

Inhibitors of the Abl kinase directed at either the ATP- or myristate-binding site.

Fabbro D, Manley PW, Jahnke W, Liebetanz J, Szyttenholm A, Fendrich G, Strauss A, Zhang J, Gray NS, Adrian F, Warmuth M, Pelle X, Grotzfeld R, Berst F, Marzinzik A, Cowan-Jacob SW, Furet P, Mestan J. Fabbro D, et al. Among authors: fendrich g. Biochim Biophys Acta. 2010 Mar;1804(3):454-62. doi: 10.1016/j.bbapap.2009.12.009. Biochim Biophys Acta. 2010. PMID: 20152788

8

Binding or bending: distinction of allosteric Abl kinase agonists from antagonists by an NMR-based conformational assay.

Jahnke W, Grotzfeld RM, Pellé X, Strauss A, Fendrich G, Cowan-Jacob SW, Cotesta S, Fabbro D, Furet P, Mestan J, Marzinzik AL. Jahnke W, et al. Among authors: fendrich g. J Am Chem Soc. 2010 May 26;132(20):7043-8. doi: 10.1021/ja101837n. J Am Chem Soc. 2010. PMID: 20450175

9

Backbone NMR resonance assignment of the Abelson kinase domain in complex with imatinib.

Vajpai N, Strauss A, Fendrich G, Cowan-Jacob SW, Manley PW, Jahnke W, Grzesiek S. Vajpai N, et al. Among authors: fendrich g. Biomol NMR Assign. 2008 Jun;2(1):41-2. doi: 10.1007/s12104-008-9079-7. Epub 2008 Mar 5. Biomol NMR Assign. 2008. PMID: 19636920

10

Amino-acid-type selective isotope labeling of proteins expressed in Baculovirus-infected insect cells useful for NMR studies.

Strauss A, Bitsch F, Cutting B, Fendrich G, Graff P, Liebetanz J, Zurini M, Jahnke W. Strauss A, et al. Among authors: fendrich g. J Biomol NMR. 2003 Aug;26(4):367-72. doi: 10.1023/a:1024013111478. J Biomol NMR. 2003. PMID: 12815263

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