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Adoptive T-cell therapy for cancer in the United kingdom: a review of activity for the British Society of Gene and Cell Therapy annual meeting 2015.
Gilham DE, Anderson J, Bridgeman JS, Hawkins RE, Exley MA, Stauss H, Maher J, Pule M, Sewell AK, Bendle G, Lee S, Qasim W, Thrasher A, Morris E. Gilham DE, et al. Among authors: sewell ak. Hum Gene Ther. 2015 May;26(5):276-85. doi: 10.1089/hum.2015.024. Hum Gene Ther. 2015. PMID: 25860661 Free PMC article. Review.
Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination.
Pageon SV, Tabarin T, Yamamoto Y, Ma Y, Nicovich PR, Bridgeman JS, Cohnen A, Benzing C, Gao Y, Crowther MD, Tungatt K, Dolton G, Sewell AK, Price DA, Acuto O, Parton RG, Gooding JJ, Rossy J, Rossjohn J, Gaus K. Pageon SV, et al. Among authors: sewell ak. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5454-63. doi: 10.1073/pnas.1607436113. Epub 2016 Aug 29. Proc Natl Acad Sci U S A. 2016. PMID: 27573839 Free PMC article.
CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor.
Clement M, Knezevic L, Dockree T, McLaren JE, Ladell K, Miners KL, Llewellyn-Lacey S, Rubina A, Francis O, Cole DK, Sewell AK, Bridgeman JS, Price DA, van den Berg HA, Wooldridge L. Clement M, et al. Among authors: sewell ak. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2019639118. doi: 10.1073/pnas.2019639118. Proc Natl Acad Sci U S A. 2021. PMID: 34272276 Free PMC article.
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies.
Ferrari M, Righi M, Baldan V, Wawrzyniecka P, Bulek A, Kinna A, Ma B, Bughda R, Akbar Z, Srivastava S, Gannon I, Robson M, Sillibourne J, Jha R, El-Kholy M, Amin OM, Kokalaki E, Banani MA, Hussain R, Day W, Lim WC, Ghongane P, Hopkins JR, Jungherz D, Herling M, Welin M, Surade S, Dyson M, McCafferty J, Logan D, Cordoba S, Thomas S, Sewell A, Maciocia P, Onuoha S, Pule M. Ferrari M, et al. Nat Commun. 2024 Feb 21;15(1):1583. doi: 10.1038/s41467-024-45854-3. Nat Commun. 2024. PMID: 38383515 Free PMC article.
212 results