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Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma.
Mann MB, Black MA, Jones DJ, Ward JM, Yew CC, Newberg JY, Dupuy AJ, Rust AG, Bosenberg MW, McMahon M, Print CG, Copeland NG, Jenkins NA. Mann MB, et al. Among authors: mcmahon m. Nat Genet. 2015 May;47(5):486-95. doi: 10.1038/ng.3275. Epub 2015 Apr 13. Nat Genet. 2015. PMID: 25848750 Free PMC article.
Oncogenic BRAF(V600E) inhibits BIM expression to promote melanoma cell survival.
Cartlidge RA, Thomas GR, Cagnol S, Jong KA, Molton SA, Finch AJ, McMahon M. Cartlidge RA, et al. Among authors: mcmahon m. Pigment Cell Melanoma Res. 2008 Oct;21(5):534-44. doi: 10.1111/j.1755-148X.2008.00491.x. Epub 2007 Jul 28. Pigment Cell Melanoma Res. 2008. PMID: 18715233 Free PMC article.
Braf(V600E) cooperates with Pten loss to induce metastatic melanoma.
Dankort D, Curley DP, Cartlidge RA, Nelson B, Karnezis AN, Damsky WE Jr, You MJ, DePinho RA, McMahon M, Bosenberg M. Dankort D, et al. Among authors: mcmahon m. Nat Genet. 2009 May;41(5):544-52. doi: 10.1038/ng.356. Epub 2009 Mar 12. Nat Genet. 2009. PMID: 19282848 Free PMC article.
β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas.
Damsky WE, Curley DP, Santhanakrishnan M, Rosenbaum LE, Platt JT, Gould Rothberg BE, Taketo MM, Dankort D, Rimm DL, McMahon M, Bosenberg M. Damsky WE, et al. Among authors: mcmahon m. Cancer Cell. 2011 Dec 13;20(6):741-54. doi: 10.1016/j.ccr.2011.10.030. Cancer Cell. 2011. PMID: 22172720 Free PMC article.
An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background.
Mitra D, Luo X, Morgan A, Wang J, Hoang MP, Lo J, Guerrero CR, Lennerz JK, Mihm MC, Wargo JA, Robinson KC, Devi SP, Vanover JC, D'Orazio JA, McMahon M, Bosenberg MW, Haigis KM, Haber DA, Wang Y, Fisher DE. Mitra D, et al. Among authors: mcmahon m. Nature. 2012 Nov 15;491(7424):449-53. doi: 10.1038/nature11624. Epub 2012 Oct 31. Nature. 2012. PMID: 23123854 Free PMC article.
Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.
Yuan P, Ito K, Perez-Lorenzo R, Del Guzzo C, Lee JH, Shen CH, Bosenberg MW, McMahon M, Cantley LC, Zheng B. Yuan P, et al. Among authors: mcmahon m. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18226-31. doi: 10.1073/pnas.1317577110. Epub 2013 Oct 21. Proc Natl Acad Sci U S A. 2013. PMID: 24145418 Free PMC article.
1,479 results