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Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis.
von Karstedt S, Conti A, Nobis M, Montinaro A, Hartwig T, Lemke J, Legler K, Annewanter F, Campbell AD, Taraborrelli L, Grosse-Wilde A, Coy JF, El-Bahrawy MA, Bergmann F, Koschny R, Werner J, Ganten TM, Schweiger T, Hoetzenecker K, Kenessey I, Hegedüs B, Bergmann M, Hauser C, Egberts JH, Becker T, Röcken C, Kalthoff H, Trauzold A, Anderson KI, Sansom OJ, Walczak H. von Karstedt S, et al. Among authors: legler k. Cancer Cell. 2015 Apr 13;27(4):561-73. doi: 10.1016/j.ccell.2015.02.014. Epub 2015 Apr 2. Cancer Cell. 2015. PMID: 25843002 Free PMC article.
Inhibition of IL-6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer.
Goumas FA, Holmer R, Egberts JH, Gontarewicz A, Heneweer C, Geisen U, Hauser C, Mende MM, Legler K, Röcken C, Becker T, Waetzig GH, Rose-John S, Kalthoff H. Goumas FA, et al. Among authors: legler k. Int J Cancer. 2015 Sep 1;137(5):1035-46. doi: 10.1002/ijc.29445. Epub 2015 Jan 29. Int J Cancer. 2015. PMID: 25604508 Free article.
Role of CCL20 mediated immune cell recruitment in NF-κB mediated TRAIL resistance of pancreatic cancer.
Geismann C, Grohmann F, Dreher A, Häsler R, Rosenstiel P, Legler K, Hauser C, Egberts JH, Sipos B, Schreiber S, Linkermann A, Hassan Z, Schneider G, Schäfer H, Arlt A. Geismann C, et al. Among authors: legler k. Biochim Biophys Acta Mol Cell Res. 2017 May;1864(5):782-796. doi: 10.1016/j.bbamcr.2017.02.005. Epub 2017 Feb 8. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28188806 Free article.
Role of protein glycosylation in cancer metastasis.
Oliveira-Ferrer L, Legler K, Milde-Langosch K. Oliveira-Ferrer L, et al. Among authors: legler k. Semin Cancer Biol. 2017 Jun;44:141-152. doi: 10.1016/j.semcancer.2017.03.002. Epub 2017 Mar 16. Semin Cancer Biol. 2017. PMID: 28315783 Review.
The role of the desmosomal protein desmocollin 2 in tumour progression in triple negative breast cancer patients.
Reimer F, Bryan S, Legler K, Karn T, Eppenberger-Castori S, Matschke J, Pereira-Veiga T, Wikman H, Witzel I, Müller V, Schmalfeldt B, Milde-Langosch K, Schumacher U, Stürken C, Oliveira-Ferrer L. Reimer F, et al. Among authors: legler k. Cancer Cell Int. 2023 Mar 16;23(1):47. doi: 10.1186/s12935-023-02896-9. Cancer Cell Int. 2023. PMID: 36927383 Free PMC article.
29 results