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An immunosuppressive antibody-drug conjugate.
Wang RE, Liu T, Wang Y, Cao Y, Du J, Luo X, Deshmukh V, Kim CH, Lawson BR, Tremblay MS, Young TS, Kazane SA, Wang F, Schultz PG. Wang RE, et al. Among authors: kazane sa. J Am Chem Soc. 2015 Mar 11;137(9):3229-32. doi: 10.1021/jacs.5b00620. Epub 2015 Feb 27. J Am Chem Soc. 2015. PMID: 25699419 Free PMC article.
Multiformat T-cell-engaging bispecific antibodies targeting human breast cancers.
Cao Y, Axup JY, Ma JS, Wang RE, Choi S, Tardif V, Lim RK, Pugh HM, Lawson BR, Welzel G, Kazane SA, Sun Y, Tian F, Srinagesh S, Javahishvili T, Schultz PG, Kim CH. Cao Y, et al. Among authors: kazane sa. Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7022-7. doi: 10.1002/anie.201500799. Epub 2015 Apr 27. Angew Chem Int Ed Engl. 2015. PMID: 25919418 Free PMC article.
Versatile strategy for controlling the specificity and activity of engineered T cells.
Ma JS, Kim JY, Kazane SA, Choi SH, Yun HY, Kim MS, Rodgers DT, Pugh HM, Singer O, Sun SB, Fonslow BR, Kochenderfer JN, Wright TM, Schultz PG, Young TS, Kim CH, Cao Y. Ma JS, et al. Among authors: kazane sa. Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):E450-8. doi: 10.1073/pnas.1524193113. Epub 2016 Jan 12. Proc Natl Acad Sci U S A. 2016. PMID: 26759368 Free PMC article.
Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer.
Cao Y, Rodgers DT, Du J, Ahmad I, Hampton EN, Ma JS, Mazagova M, Choi SH, Yun HY, Xiao H, Yang P, Luo X, Lim RK, Pugh HM, Wang F, Kazane SA, Wright TM, Kim CH, Schultz PG, Young TS. Cao Y, et al. Among authors: kazane sa. Angew Chem Int Ed Engl. 2016 Jun 20;55(26):7520-4. doi: 10.1002/anie.201601902. Epub 2016 May 4. Angew Chem Int Ed Engl. 2016. PMID: 27145250 Free PMC article.
Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune Cells via an Antibody-drug Conjugate.
Yu S, Pearson AD, Lim RK, Rodgers DT, Li S, Parker HB, Weglarz M, Hampton EN, Bollong MJ, Shen J, Zambaldo C, Wang D, Woods AK, Wright TM, Schultz PG, Kazane SA, Young TS, Tremblay MS. Yu S, et al. Among authors: kazane sa. Mol Ther. 2016 Dec;24(12):2078-2089. doi: 10.1038/mt.2016.175. Epub 2016 Oct 12. Mol Ther. 2016. PMID: 27731313 Free PMC article.
A CXCR4-targeted site-specific antibody-drug conjugate.
Kularatne SA, Deshmukh V, Ma J, Tardif V, Lim RK, Pugh HM, Sun Y, Manibusan A, Sellers AJ, Barnett RS, Srinagesh S, Forsyth JS, Hassenpflug W, Tian F, Javahishvili T, Felding-Habermann B, Lawson BR, Kazane SA, Schultz PG. Kularatne SA, et al. Among authors: kazane sa. Angew Chem Int Ed Engl. 2014 Oct 27;53(44):11863-7. doi: 10.1002/anie.201408103. Epub 2014 Sep 11. Angew Chem Int Ed Engl. 2014. PMID: 25213874 Free PMC article.
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