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Targeting DDX3 with a small molecule inhibitor for lung cancer therapy.
Bol GM, Vesuna F, Xie M, Zeng J, Aziz K, Gandhi N, Levine A, Irving A, Korz D, Tantravedi S, Heerma van Voss MR, Gabrielson K, Bordt EA, Polster BM, Cope L, van der Groep P, Kondaskar A, Rudek MA, Hosmane RS, van der Wall E, van Diest PJ, Tran PT, Raman V. Bol GM, et al. Among authors: tantravedi s. EMBO Mol Med. 2015 May;7(5):648-69. doi: 10.15252/emmm.201404368. EMBO Mol Med. 2015. PMID: 25820276 Free PMC article.
Targeting mitochondrial translation by inhibiting DDX3: a novel radiosensitization strategy for cancer treatment.
Heerma van Voss MR, Vesuna F, Bol GM, Afzal J, Tantravedi S, Bergman Y, Kammers K, Lehar M, Malek R, Ballew M, Ter Hoeve N, Abou D, Thorek D, Berlinicke C, Yazdankhah M, Sinha D, Le A, Abrahams R, Tran PT, van Diest PJ, Raman V. Heerma van Voss MR, et al. Among authors: tantravedi s. Oncogene. 2018 Jan 4;37(1):63-74. doi: 10.1038/onc.2017.308. Epub 2017 Sep 4. Oncogene. 2018. PMID: 28869602 Free PMC article.
PLGA nanoparticle formulation of RK-33: an RNA helicase inhibitor against DDX3.
Bol GM, Khan R, Heerma van Voss MR, Tantravedi S, Korz D, Kato Y, Raman V. Bol GM, et al. Among authors: tantravedi s. Cancer Chemother Pharmacol. 2015 Oct;76(4):821-7. doi: 10.1007/s00280-015-2851-3. Epub 2015 Sep 2. Cancer Chemother Pharmacol. 2015. PMID: 26330329 Free PMC article.
RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3.
Xie M, Vesuna F, Tantravedi S, Bol GM, Heerma van Voss MR, Nugent K, Malek R, Gabrielson K, van Diest PJ, Tran PT, Raman V. Xie M, et al. Among authors: tantravedi s. Cancer Res. 2016 Nov 1;76(21):6340-6350. doi: 10.1158/0008-5472.CAN-16-0440. Epub 2016 Sep 12. Cancer Res. 2016. PMID: 27634756 Free PMC article.
Role of DDX3 in the pathogenesis of inflammatory bowel disease.
Tantravedi S, Vesuna F, Winnard PT Jr, Van Voss MRH, Van Diest PJ, Raman V. Tantravedi S, et al. Oncotarget. 2017 Dec 15;8(70):115280-115289. doi: 10.18632/oncotarget.23323. eCollection 2017 Dec 29. Oncotarget. 2017. PMID: 29383159 Free PMC article.
Global Effects of DDX3 Inhibition on Cell Cycle Regulation Identified by a Combined Phosphoproteomics and Single Cell Tracking Approach.
Heerma van Voss MR, Kammers K, Vesuna F, Brilliant J, Bergman Y, Tantravedi S, Wu X, Cole RN, Holland A, van Diest PJ, Raman V. Heerma van Voss MR, et al. Among authors: tantravedi s. Transl Oncol. 2018 Jun;11(3):755-763. doi: 10.1016/j.tranon.2018.04.001. Epub 2018 Apr 24. Transl Oncol. 2018. PMID: 29684792 Free PMC article.
Targeting DDX3 in Medulloblastoma Using the Small Molecule Inhibitor RK-33.
Tantravedi S, Vesuna F, Winnard PT Jr, Martin A, Lim M, Eberhart CG, Berlinicke C, Raabe E, van Diest PJ, Raman V. Tantravedi S, et al. Transl Oncol. 2019 Jan;12(1):96-105. doi: 10.1016/j.tranon.2018.09.002. Epub 2018 Oct 3. Transl Oncol. 2019. PMID: 30292066 Free PMC article.
Analogs of iso-azepinomycin as potential transition-state analog inhibitors of guanase: synthesis, biochemical screening, and structure-activity correlations of various selectively substituted imidazo[4,5-e][1,4]diazepines.
Tantravedi S, Chakraborty S, Shah NH, Fishbein JC, Hosmane RS. Tantravedi S, et al. Bioorg Med Chem. 2013 Sep 1;21(17):4893-903. doi: 10.1016/j.bmc.2013.06.069. Epub 2013 Jul 11. Bioorg Med Chem. 2013. PMID: 23891230 Free PMC article.