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Targeting DDX3 with a small molecule inhibitor for lung cancer therapy.
Bol GM, Vesuna F, Xie M, Zeng J, Aziz K, Gandhi N, Levine A, Irving A, Korz D, Tantravedi S, Heerma van Voss MR, Gabrielson K, Bordt EA, Polster BM, Cope L, van der Groep P, Kondaskar A, Rudek MA, Hosmane RS, van der Wall E, van Diest PJ, Tran PT, Raman V. Bol GM, et al. Among authors: gabrielson k. EMBO Mol Med. 2015 May;7(5):648-69. doi: 10.15252/emmm.201404368. EMBO Mol Med. 2015. PMID: 25820276 Free PMC article.
An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.
Feldmann G, Fendrich V, McGovern K, Bedja D, Bisht S, Alvarez H, Koorstra JB, Habbe N, Karikari C, Mullendore M, Gabrielson KL, Sharma R, Matsui W, Maitra A. Feldmann G, et al. Among authors: gabrielson kl. Mol Cancer Ther. 2008 Sep;7(9):2725-35. doi: 10.1158/1535-7163.MCT-08-0573. Mol Cancer Ther. 2008. PMID: 18790753 Free PMC article.
A preclinical murine model for the early detection of radiation-induced brain injury using magnetic resonance imaging and behavioral tests for learning and memory: with applications for the evaluation of possible stem cell imaging agents and therapies.
Ngen EJ, Wang L, Gandhi N, Kato Y, Armour M, Zhu W, Wong J, Gabrielson KL, Artemov D. Ngen EJ, et al. J Neurooncol. 2016 Jun;128(2):225-33. doi: 10.1007/s11060-016-2111-3. Epub 2016 Mar 28. J Neurooncol. 2016. PMID: 27021492
RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3.
Xie M, Vesuna F, Tantravedi S, Bol GM, Heerma van Voss MR, Nugent K, Malek R, Gabrielson K, van Diest PJ, Tran PT, Raman V. Xie M, et al. Among authors: gabrielson k. Cancer Res. 2016 Nov 1;76(21):6340-6350. doi: 10.1158/0008-5472.CAN-16-0440. Epub 2016 Sep 12. Cancer Res. 2016. PMID: 27634756 Free PMC article.
CRYβB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer.
Yan Y, Narayan A, Cho S, Cheng Z, Liu JO, Zhu H, Wang G, Wharram B, Lisok A, Brummet M, Saeki H, Huang T, Gabrielson K, Gabrielson E, Cope L, Kanaan YM, Afsari A, Naab T, Yfantis HG, Ambs S, Pomper MG, Sukumar S, Merino VF. Yan Y, et al. Among authors: gabrielson k, gabrielson e. Oncogene. 2021 Sep;40(38):5752-5763. doi: 10.1038/s41388-021-01975-3. Epub 2021 Aug 2. Oncogene. 2021. PMID: 34341513 Free PMC article.
FLASH Effects Induced by Orthovoltage X-Rays.
Miles D, Sforza D, Wong JW, Gabrielson K, Aziz K, Mahesh M, Coulter JB, Siddiqui I, Tran PT, Viswanathan AN, Rezaee M. Miles D, et al. Among authors: gabrielson k. Int J Radiat Oncol Biol Phys. 2023 Nov 15;117(4):1018-1027. doi: 10.1016/j.ijrobp.2023.06.006. Epub 2023 Jun 25. Int J Radiat Oncol Biol Phys. 2023. PMID: 37364800
TNIK inhibition sensitizes TNIK-overexpressing lung squamous cell carcinoma to radiotherapy.
Nguyen T, Carrieri FA, Connis N, Lafargue A, Chang J, Chan A, Shetty AC, Song Y, Hoang T, Jagtap S, Chowdhury DD, Khan MA, Gabrielson KL, Rezaee M, Torres-Ayuso P, Brognard J, Hann CL, Tran PT. Nguyen T, et al. Among authors: gabrielson kl. Mol Cancer Ther. 2024 Apr 27. doi: 10.1158/1535-7163.MCT-23-0412. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38670554
155 results