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Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo.
Borkin D, He S, Miao H, Kempinska K, Pollock J, Chase J, Purohit T, Malik B, Zhao T, Wang J, Wen B, Zong H, Jones M, Danet-Desnoyers G, Guzman ML, Talpaz M, Bixby DL, Sun D, Hess JL, Muntean AG, Maillard I, Cierpicki T, Grembecka J. Borkin D, et al. Among authors: maillard i. Cancer Cell. 2015 Apr 13;27(4):589-602. doi: 10.1016/j.ccell.2015.02.016. Epub 2015 Mar 26. Cancer Cell. 2015. PMID: 25817203 Free PMC article.
Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia.
Keeshan K, He Y, Wouters BJ, Shestova O, Xu L, Sai H, Rodriguez CG, Maillard I, Tobias JW, Valk P, Carroll M, Aster JC, Delwel R, Pear WS. Keeshan K, et al. Among authors: maillard i. Cancer Cell. 2006 Nov;10(5):401-11. doi: 10.1016/j.ccr.2006.09.012. Cancer Cell. 2006. PMID: 17097562 Free PMC article.
The role of menin in hematopoiesis.
Maillard I, Hess JL. Maillard I, et al. Adv Exp Med Biol. 2009;668:51-7. doi: 10.1007/978-1-4419-1664-8_5. Adv Exp Med Biol. 2009. PMID: 20175452 Free PMC article.
179 results