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Page 1
Anthelmintic activity in vivo of epiisopiloturine against juvenile and adult worms of Schistosoma mansoni.
Guimarães MA, de Oliveira RN, Véras LM, Lima DF, Campelo YD, Campos SA, Kuckelhaus SA, Pinto PL, Eaton P, Mafud AC, Mascarenhas YP, Allegretti SM, de Moraes J, Lolić A, Verbić T, Leite JR. Guimarães MA, et al. Among authors: mascarenhas yp. PLoS Negl Trop Dis. 2015 Mar 27;9(3):e0003656. doi: 10.1371/journal.pntd.0003656. eCollection 2015 Mar. PLoS Negl Trop Dis. 2015. PMID: 25816129 Free PMC article.
Synergistic effects of in vitro combinations of piplartine, epiisopiloturine and praziquantel against Schistosoma mansoni.
Campelo YDM, Mafud AC, Véras LMC, Guimarães MA, Yamaguchi LF, Lima DF, Arcanjo DDR, Kato MJ, Mendonça RZ, Pinto PLS, Mascarenhas YP, Silva MPN, de Moraes J, Eaton P, de Souza de Almeida Leite JR. Campelo YDM, et al. Among authors: mascarenhas yp. Biomed Pharmacother. 2017 Apr;88:488-499. doi: 10.1016/j.biopha.2016.12.057. Epub 2017 Jan 23. Biomed Pharmacother. 2017. PMID: 28126674
Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity.
Guimarães MA, de Oliveira RN, de Almeida RL, Mafud AC, Sarkis ALV, Ganassin R, da Silva MP, Roquini DB, Veras LM, Sawada TCH, Ropke CD, Muehlmann LA, Joanitti GA, Kuckelhaus SAS, Allegretti SM, Mascarenhas YP, de Moraes J, Leite JRSA. Guimarães MA, et al. Among authors: mascarenhas yp. PLoS One. 2018 May 11;13(5):e0196667. doi: 10.1371/journal.pone.0196667. eCollection 2018. PLoS One. 2018. PMID: 29750792 Free PMC article.
Industrial Scale Isolation, Structural and Spectroscopic Characterization of Epiisopiloturine from Pilocarpus microphyllus Stapf Leaves: A Promising Alkaloid against Schistosomiasis.
Véras LM, Cunha VR, Lima FC, Guimarães MA, Vieira MM, Campelo YD, Sakai VY, Lima DF, Carvalho PS Jr, Ellena JA, Silva PR, Vasconcelos LC, Godejohann M, Petrilli HM, Constantino VR, Mascarenhas YP, de Souza de Almeida Leite JR. Véras LM, et al. Among authors: mascarenhas yp. PLoS One. 2013 Jun 26;8(6):e66702. doi: 10.1371/journal.pone.0066702. Print 2013. PLoS One. 2013. PMID: 23840522 Free PMC article.
Anthelmintic, Antibacterial and Cytotoxicity Activity of Imidazole Alkaloids from Pilocarpus microphyllus Leaves.
Rocha JA, Andrade IM, Véras LM, Quelemes PV, Lima DF, Soares MJ, Pinto PL, Mayo SJ, Ivanova G, Rangel M, Correia M, Mafud AC, Mascarenhas YP, Delerue-Matos C, de Moraes J, Eaton P, Leite JR. Rocha JA, et al. Among authors: mascarenhas yp. Phytother Res. 2017 Apr;31(4):624-630. doi: 10.1002/ptr.5771. Epub 2017 Jan 23. Phytother Res. 2017. PMID: 28111828
Self-nanoemulsifying drug-delivery systems improve oral absorption and antischistosomal activity of epiisopiloturine.
de Lima LI, Py-Daniel KR, Guimarães MA, Muehlmann LA, Mafud AC, Mascarenhas YP, Moraes J, de Souza de Almeida Leite JR, Jiang CS, Azevedo RB, Figueiró Longo JP. de Lima LI, et al. Among authors: mascarenhas yp. Nanomedicine (Lond). 2018 Apr 1;13(7):689-702. doi: 10.2217/nnm-2017-0308. Epub 2018 Mar 22. Nanomedicine (Lond). 2018. PMID: 29564947
Structural parameters, molecular properties, and biological evaluation of some terpenes targeting Schistosoma mansoni parasite.
Mafud AC, Silva MP, Monteiro DC, Oliveira MF, Resende JG, Coelho ML, de Sousa DP, Mendonça RZ, Pinto PL, Freitas RM, Mascarenhas YP, de Moraes J. Mafud AC, et al. Among authors: mascarenhas yp. Chem Biol Interact. 2016 Jan 25;244:129-39. doi: 10.1016/j.cbi.2015.12.003. Epub 2015 Dec 15. Chem Biol Interact. 2016. PMID: 26697994
Antiparasitic, structural, pharmacokinetic, and toxicological properties of riparin derivatives.
Mafud AC, Silva MPN, Nunes GBL, de Oliveira MAR, Batista LF, Rubio TI, Mengarda AC, Lago EM, Xavier RP, Gutierrez SJC, Pinto PLS, da Silva Filho AA, Mascarenhas YP, de Moraes J. Mafud AC, et al. Among authors: mascarenhas yp. Toxicol In Vitro. 2018 Aug;50:1-10. doi: 10.1016/j.tiv.2018.02.012. Epub 2018 Feb 22. Toxicol In Vitro. 2018. PMID: 29476885
Structure⁻Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells.
Campelo Y, Ombredane A, Vasconcelos AG, Albuquerque L, Moreira DC, Plácido A, Rocha J, Hilarion Fokoue H, Yamaguchi L, Mafud A, Mascarenhas YP, Delerue-Matos C, Borges T, Joanitti GA, Arcanjo D, Kato MJ, Kuckelhaus SAS, Silva MPN, Moraes J, Leite JRSA. Campelo Y, et al. Among authors: mascarenhas yp. Int J Mol Sci. 2018 Jun 19;19(6):1802. doi: 10.3390/ijms19061802. Int J Mol Sci. 2018. PMID: 29921756 Free PMC article.
47 results